Reactome | phospho-H3-X [nucleoplasm]

phospho-H3-X [nucleoplasm]

Stable Identifier

R-GGA-5625858

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

p-T12,MeK-H3F3A, P84247

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
  - Signaling by Rho GTPases (Gallus gallus)
    - RHO GTPase Effectors (Gallus gallus)
      - RHO GTPases activate PKNs (Gallus gallus)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Gallus gallus)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        phospho-H3-X [nucleoplasm] (Gallus gallus)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        phospho-H3-X [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:P84247

Gene Names

H3-X

Reference Genes

BioGPS Gene:396233 H3-X

BioGPS Gene:427887 H3-X

ENSEMBL:ENSGALG00000002286

ENSEMBL:ENSGALG00000020078 H3-X

ENSEMBL:ENSGALG00000054599 H3-X

ENSEMBL:ENSGALG00010008224.1 H3-X

ENSEMBL:ENSGALG00010017538.1 H3-X

ENSEMBL:ENSGALG00010029787.1 H3-X

ENSEMBL:ENSGALG00015001201 H3-X

ENSEMBL:ENSGALG00015006073 H3-X

ENSEMBL:ENSGALG00015024464 H3-X

KEGG Gene (Gallus gallus):396233 H3-X

KEGG Gene (Gallus gallus):427887 H3-X

Monarch:396233 H3-X

Monarch:427887 H3-X

NCBI Gene:396233 H3-X

NCBI Gene:427887 H3-X

Reference Transcript

Other Identifiers

100859629

396233

427887

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005694

GO:0030527

GO:0043226

GO:0046982

GT_A_87_P008765

GT_A_87_P052556

GT_A_87_P097636

GT_A_87_P118138

GT_A_87_P189338

GT_Sp_Chicken_CO762256_7770

GT_Xhyb_Chicken_CN219025_1269

GT_Xhyb_Chicken_CN222993_2538

GT_Xhyb_Chicken_CN233395_3436

Gga.12912.1.S1_at

Gga.4770.1.S1_at

Gga.5274.1.S1_at

Gga.5274.2.S1_a_at

Participates

as a member of

p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)

Other forms of this molecule

H3-X [nucleoplasm]

phospho-H3-X [nucleoplasm]

H3-X [nucleoplasm]

phospho-H3-X [nucleoplasm]

H3-X [nucleoplasm]

Inferred From

p-T12,MeK-H3F3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_990627.1, NP_001026653.2

Ensembl

ENSGALG00010008224, ENSGALT00010072060, ENSGALT00010019662, ENSGALT00010042395, ENSGALP00010044750, ENSGALG00010029787, ENSGALP00010011211, ENSGALG00010017538, ENSGALP00010024885

PRO

P84247

PDB

1PDQ