Reactome | phospho-H3-VII [nucleoplasm]

phospho-H3-VII [nucleoplasm]

Stable Identifier

R-GGA-5625857

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

p-T12,MeK-HIST2H3A, P84229

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
  - Signaling by Rho GTPases (Gallus gallus)
    - RHO GTPase Effectors (Gallus gallus)
      - RHO GTPases activate PKNs (Gallus gallus)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Gallus gallus)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        phospho-H3-VII [nucleoplasm] (Gallus gallus)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Gallus gallus)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)
        
        phospho-H3-VII [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:P84229

Gene Names

H3-VII

Reference Genes

BioGPS Gene:100857439 H3-VII

BioGPS Gene:100858681 H3-VII

BioGPS Gene:417953 H3-VII

BioGPS Gene:769852 H3-VII

BioGPS Gene:770022 H3-VII

CTD Gene:100858681 H3-VII

ENSEMBL:ENSGALG00000027064

ENSEMBL:ENSGALG00000038969 H3-VII

ENSEMBL:ENSGALG00000048231 H3-VII

ENSEMBL:ENSGALG00000051325 H3-VII

ENSEMBL:ENSGALG00010012169.1 H3-VII

ENSEMBL:ENSGALG00010012266.1 H3-VII

ENSEMBL:ENSGALG00010012277.1 H3-VII

ENSEMBL:ENSGALG00010012338.1 H3-VII

ENSEMBL:ENSGALG00010013592.1 H3-VII

ENSEMBL:ENSGALG00015009748 H3-VII

ENSEMBL:ENSGALG00015009771 H3-VII

ENSEMBL:ENSGALG00015009789 H3-VII

ENSEMBL:ENSGALG00015009792 H3-VII

ENSEMBL:ENSGALG00015009818 H3-VII

KEGG Gene (Gallus gallus):100857439 H3-VII

KEGG Gene (Gallus gallus):100858681 H3-VII

KEGG Gene (Gallus gallus):417953 H3-VII

KEGG Gene (Gallus gallus):768333 H3-VII

KEGG Gene (Gallus gallus):769809 H3-VII

KEGG Gene (Gallus gallus):769852 H3-VII

KEGG Gene (Gallus gallus):770022 H3-VII

Monarch:100857439 H3-VII

Monarch:100858681 H3-VII

Monarch:417953 H3-VII

Monarch:769852 H3-VII

Monarch:770022 H3-VII

NCBI Gene:100857439 H3-VII

NCBI Gene:100858681 H3-VII

NCBI Gene:417953 H3-VII

NCBI Gene:769852 H3-VII

NCBI Gene:770022 H3-VII

Reference Transcript

Other Identifiers

100857439

100858681

121106438

121110383

417953

768333

769852

770022

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005694

GO:0030527

GO:0043226

GO:0046982

GT_A_87_P004039

GT_A_87_P052531

GT_A_87_P052571

GT_A_87_P052609

GT_A_87_P086856

GT_A_87_P086861

GT_A_87_P106898

GT_A_87_P106904

GT_A_87_P106928

GT_A_87_P106998

Gga.5576.1.S1_a_at

Gga.6103.1.S1_at

Gga.6103.1.S1_x_at

GgaAffx.23665.1.S1_at

GgaAffx.23665.1.S1_x_at

GgaAffx.23666.1.A1_at

GgaAffx.23666.1.S1_at

Participates

as a member of

p-T12,MeK-10-H3 [nucleoplasm] (Gallus gallus)

Other forms of this molecule

H3-VII [nucleoplasm]

phospho-H3-VII [nucleoplasm]

H3-VII [nucleoplasm]

phospho-H3-VII [nucleoplasm]

H3-VII [nucleoplasm]

Inferred From

p-T12,MeK-HIST2H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_416193.2, NP_001268409.1, XP_015144926.1, XP_001233028.1, NP_001268438.1, XP_015144912.1, XP_001232833.1

Ensembl

ENSGALG00010013592, ENSGALT00010029534, ENSGALT00010029379, ENSGALT00010029400, ENSGALP00010017166, ENSGALP00010017077, ENSGALT00010029191, ENSGALP00010019354, ENSGALG00010012338, ENSGALP00010017063, ENSGALP00010017073, ENSGALG00010012169, ENSGALG00010012277, ENSGALG00010012266, ENSGALP00010016931, ENSGALT00010032659, ENSGALT00010029395

PRO

P84229

PDB

7BY0, 2HIO, 7BXT, 1TZY, 1HQ3, 3C9K, 1HIO, 1EQZ, 2ARO

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