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VCP hexamer [cytosol]
Stable Identifier
R-GGA-5362364
Type
Complex
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
KEAP1-NFE2L2 pathway (Gallus gallus)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Gallus gallus)
NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Regulation of T cell activation by CD28 family (Gallus gallus)
Co-inhibition by PD-1 (Gallus gallus)
Regulation of PD-L1(CD274) expression (Gallus gallus)
Regulation of PD-L1(CD274) Post-translational modification (Gallus gallus)
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) (Gallus gallus)
Active transport of ubiquitinated CD274 from ER to cytosol (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Ubiquitination of CD274 by ERAD complex (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
p-S195-CD274 binds ERAD complex (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Gallus gallus)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Gallus gallus)
Deglycosylation complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Neddylation (Gallus gallus)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Gallus gallus)
NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog ligand biogenesis (Gallus gallus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Gallus gallus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
SYVN1 ubiquitinates Hh C-terminal fragments (Gallus gallus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Gallus gallus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 6
VCP [cytosol]
(Gallus gallus)
Participates
as a component of
VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide-Ala [cytosol] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
Deglycosylation complex [endoplasmic reticulum membrane] (Gallus gallus)
Inferred From
VCP hexamer [cytosol]
(Homo sapiens)
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