Reactome | phospho-PAK2 [cytosol]

phospho-PAK2 [cytosol]

Stable Identifier

R-GGA-5218705

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

p-Y130,S141,T402-PAK2, E1BS97

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by Receptor Tyrosine Kinases (Gallus gallus)
  - Signaling by VEGF (Gallus gallus)
    - VEGFA-VEGFR2 Pathway (Gallus gallus)
      - FYN phosphorylates PAK2 (Gallus gallus)
        
        VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
        
        p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Gallus gallus)
        
        p-3Y-PAK2 dimer [cytosol] (Gallus gallus)
        
        phospho-PAK2 [cytosol] (Gallus gallus)
      - p38 MAPK activation by VEGFR (Gallus gallus)
        
        VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-3Y-PAK2:CDC42:GTP [plasma membrane] (Gallus gallus)
        
        p-3Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Gallus gallus)
        
        p-3Y-PAK2 dimer [cytosol] (Gallus gallus)
        
        phospho-PAK2 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:E1BS97

Gene Names

PAK2

Reference Genes

BioGPS Gene:424860 PAK2

ENSEMBL:ENSGALG00000006426

KEGG Gene (Gallus gallus):424860 PAK2

Monarch:424860 PAK2

NCBI Gene:424860 PAK2

Reference Transcript

Other Identifiers

424860

GO:0000166

GO:0000902

GO:0003674

GO:0004672

GO:0004674

GO:0005524

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0005911

GO:0006464

GO:0006468

GO:0006950

GO:0007010

GO:0007165

GO:0008150

GO:0008219

GO:0014069

GO:0016301

GO:0016310

GO:0018105

GO:0019899

GO:0019901

GO:0022607

GO:0023014

GO:0030154

GO:0030234

GO:0030296

GO:0031098

GO:0031267

GO:0032147

GO:0034330

GO:0034333

GO:0042802

GO:0042981

GO:0043066

GO:0043167

GO:0043226

GO:0046777

GO:0048365

GO:0048856

GO:0050731

GO:0050770

GO:0051493

GO:0051497

GO:0060996

GO:0061098

GO:0070830

GO:0071407

GO:0098978

GO:0150105

GO:2001238

GO:2001271

GT_A_87_P077026

GgaAffx.3992.1.S1_s_at

Participant Of

hasComponent

p-3Y-PAK2 dimer [cytosol]

Other forms of this molecule

phospho-PAK2 [plasma membrane]

PAK2 [cytosol]

phospho-PAK2 [cytosol]

Inferred From

p-Y130,S141,T402-PAK2 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 141 (in Homo sapiens)

Coordinate

141

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 402 (in Homo sapiens)

Coordinate

402

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O4'-phospho-L-tyrosine at 130 (in Homo sapiens)

Coordinate

130

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_422671.2, XP_004937052.1

OpenTargets

ENSG00000180370

Ensembl

ENSGALP00000010358, ENSGALG00000006426, ENSGALT00000010372