ceramide + H2O => stearate + sphingosine [endoplasmic reticulum]

Stable Identifier
R-GGA-433608
Type
Reaction [transition]
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

ACER1 (alkaline ceramidase 1), associated with the endoplasmic reticulum membrane, catalyzes the hydrolysis of ceramide to yield a free fatty acid (annotated here as stearate) and sphingosine. Chicken ACER1 is known only as the inferred protein product of an open reading frame found through ananlysis of the chicken genome. This reaction is inferred from its well-studied mammalian counterpart.

Participants
Participates
Catalyst Activity

N-acylsphingosine amidohydrolase activity of ACER1 [endoplasmic reticulum membrane]

Inferred From
Created
Cite Us!