sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP

Stable Identifier
R-GGA-433606
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol, endoplasmic reticulum membrane
ReviewStatus
5/5
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sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP
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SPHK1 (sphingosine kinase 1) catalyzes the reaction of sphinganine (dihydrosphingosine) and ATP to form dihydrosphingosine 1-phosphate and ADP. Chicken SPHK1 protein is known only as the inferred product of an open reading frame found through analysis of the chicken genome. This reaction is inferred from its well-studied mammalian counterpart.
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Catalyst Activity

sphinganine kinase activity of SPHK1 [cytosol]

Physical Entity
SPHK1 [cytosol] (Gallus gallus)
Activity
sphinganine kinase activity (GO:0008481)
Inferred From
SPHK1 phosphorylates sphingoid (Homo sapiens)
Created
D'Eustachio, P  (2009-08-22)
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