palmitoyl-CoA + serine => 3-dehydrosphinganine + CoASH + CO2

Stable Identifier
R-GGA-433550
Type
Reaction [transition]
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

SPTLC (serine palmitoyltransferase) enzyme complexes associated with the endoplasmic reticulum membrane catalyze the reaction of palmitoyl-CoA and serine to form 3-dehydrosphinganine. SPTLC2 and SPTLC3 polypeptides exhibit enzyme activity when either is complexed with SPTLC1. These chicken proteins are known only as the inferred products of genes predicted from the chicken genome sequence; their functional properties are inferred from those of their better-studied mammalian orthologues.

Participants
Participates
Catalyst Activity

serine C-palmitoyltransferase activity of SPTLC 2 and 3 complexes [endoplasmic reticulum membrane]

Inferred From
Created
Cite Us!