hydroxymethylbilane => uroporphyrinogen III + H2O

Stable Identifier
R-GGA-421482
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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hydroxymethylbilane => uroporphyrinogen III + H2O
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cytosolic UROS (uroporphyrinogen III synthase) catalyzes the reaction of hydroxymethylbilane to form uroporphyrinogen III and H2O. Chicken UROS is known only as the inferred product of a gene discovered by analysis of the chicken genomic DNA sequence. Its catalytic activity is inferred from the properties of its better-studied human counterpart.
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Catalyst Activity

uroporphyrinogen-III synthase activity of UROS [cytosol]

Physical Entity
UROS [cytosol] (Gallus gallus)
Activity
uroporphyrinogen-III synthase activity (GO:0004852)
Inferred From
UROS transforms HMB to URO3 (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-19)
Created
D'Eustachio, P  (2009-05-19)
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