Reactome | 2 delta-aminolevulinate => porphobilinogen + 2 H2O

2 delta-aminolevulinate => porphobilinogen + 2 H2O

Stable Identifier

R-GGA-421472

Type

Reaction [transition]

Species

Gallus gallus

Compartment

cytosol

ReviewStatus

5/5

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2 delta-aminolevulinate => porphobilinogen + 2 H2O

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Cytosolic ALAD (delta-aminolevulinate dehydratase) catalyzes the reaction of two molecules of delta-aminolevulinate to form porphobilinogen plus two molecules of water. Chicken ALAD is known only as the inferred product of a gene discovered by analysis of the chicken genomic DNA sequence. Its formation of an octamer with eight zinc ions and its catalytic activity are inferred from the properties of its better-studied human counterpart.

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