inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate

Stable Identifier
R-GGA-421179
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Cytosolic NT5C2 (5'-nucleotidase, cytosolic II) catalyzes the hydrolysis of inosine 5'-monophosphate (IMP) to yield inosine and orthophosphate. Chicken NT5C2 is known only as the predicted protein product of a cDNA; the reaction shown here is inferred from its better-studied human counterpart.

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Catalyst Activity

IMP 5'-nucleotidase activity of NT5C2 [cytosol]

Physical Entity
NT5C2 [cytosol] (Gallus gallus)
Activity
IMP 5'-nucleotidase activity (GO:0050483)
Inferred From
(d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-15)
Created
D'Eustachio, P  (2009-05-15)
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