Reactome | GRIN2C [plasma membrane]

GRIN2C [plasma membrane]

Stable Identifier

R-GGA-419560

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

GRIN2C, A0A8V1AEJ9

Locations in the PathwayBrowser

Expand all

Neuronal System (Gallus gallus)

- Protein-protein interactions at synapses (Gallus gallus)
  - Synaptic adhesion-like molecules (Gallus gallus)
    - SALM2 associate with AMPA and NMDA receptors (Gallus gallus)
      - AMPA, NMDA receptors [plasma membrane] (Gallus gallus)
        
        NMDA receptor complex [plasma membrane] (Gallus gallus)
        
        NMDA receptor [plasma membrane] (Gallus gallus)
        
        NR2 subunits [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
      - SALM2:AMPA, NMDA receptors [plasma membrane] (Gallus gallus)
        
        AMPA, NMDA receptors [plasma membrane] (Gallus gallus)
        
        NMDA receptor complex [plasma membrane] (Gallus gallus)
        
        NMDA receptor [plasma membrane] (Gallus gallus)
        
        NR2 subunits [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
- Transmission across Chemical Synapses (Gallus gallus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
    - Activation of NMDA receptors and postsynaptic events (Gallus gallus)
      - Assembly and cell surface presentation of NMDA receptors (Gallus gallus)
        
        GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Gallus gallus)
        
        GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
      - Unblocking of NMDA receptors, glutamate binding and activation (Gallus gallus)
        
        Ca2+ influx into the post-synaptic cell (Gallus gallus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V1AEJ9

Gene Names

GRIN2C

Reference Genes

BioGPS Gene:431090 GRIN2C

ENSEMBL:ENSGALG00010029671.1

Monarch:431090 GRIN2C

NCBI Gene:431090 GRIN2C

UCSC:A0A8V1AEJ9 GRIN2C

Reference Transcript

Other Identifiers

431090

GO:0004972

GO:0005216

GO:0005261

GO:0005886

GO:0006811

GO:0009611

GO:0015276

GO:0016020

GO:0017146

GO:0033058

GO:0034220

GO:0035235

GO:0038023

GO:0042177

GO:0042391

GO:0043226

GO:0045202

GO:0045211

GO:0048167

GO:0050877

GO:0050885

GO:0055085

GO:0060079

GO:0097553

GO:0098655

GO:0098839

GO:0098978

GO:1903539

GO:1904315

GT_Sp_ENSGALT00000044113_2011

GT_Sp_ENSGALT00000044113_2012

GT_Sp_ENSGALT00000044113_2020

Participates

as a member of

NR2 subunits [plasma membrane] (Gallus gallus)

as a component of

Other forms of this molecule

GRIN2C [endoplasmic reticulum membrane]

Inferred From

GRIN2C [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_040542610.1, XP_015150952.2

ENSEMBL

ENSGALP00010044451, ENSGALG00010029671, ENSGALT00010071761