Reactome | GRIN2C [plasma membrane]

GRIN2C [plasma membrane]

Stable Identifier

R-GGA-419560

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

R4GFN5

Locations in the PathwayBrowser

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Neuronal System (Gallus gallus)

- Protein-protein interactions at synapses (Gallus gallus)
  - Synaptic adhesion-like molecules (Gallus gallus)
    - SALM2 associate with AMPA and NMDA receptors (Gallus gallus)
      - AMPA, NMDA receptors [plasma membrane] (Gallus gallus)
        
        NMDA receptor complex [plasma membrane] (Gallus gallus)
        
        NMDA receptor [plasma membrane] (Gallus gallus)
        
        NR2 subunits [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
      - SALM2:AMPA, NMDA receptors [plasma membrane] (Gallus gallus)
        
        AMPA, NMDA receptors [plasma membrane] (Gallus gallus)
        
        NMDA receptor complex [plasma membrane] (Gallus gallus)
        
        NMDA receptor [plasma membrane] (Gallus gallus)
        
        NR2 subunits [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
- Transmission across Chemical Synapses (Gallus gallus)
  - Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
    - Activation of NMDA receptors and postsynaptic events (Gallus gallus)
      - Assembly and cell surface presentation of NMDA receptors (Gallus gallus)
        
        GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Gallus gallus)
        
        GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
      - Unblocking of NMDA receptors, glutamate binding and activation (Gallus gallus)
        
        Ca2+ influx into the post-synaptic cell (Gallus gallus)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2 NMDA receptors [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)
        
        GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Gallus gallus)
        
        GRIN2C [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:R4GFN5

Reference Genes

ENSEMBL:ENSGALG00000027415

UCSC:R4GFN5

Participates

as a member of

NR2 subunits [plasma membrane] (Gallus gallus)

as a component of

Other forms of this molecule

GRIN2C [endoplasmic reticulum membrane]

Inferred From

GRIN2C [plasma membrane] (Homo sapiens)

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