N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O

Stable Identifier
R-GGA-419465
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
ReviewStatus
5/5
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N-carbamoyl L-aspartate + H+ <=> (S)-dihydroorotate + H2O
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The dihydroorotase activity of cytosolic CAD hexamer catalyzes the reaction of N-carbamoyl L-aspartate to form dihydroorotate and water. The chicken enzyme is known only as the product of an open reading frame inferred from genomic sequencing; all molecular details of the reaction are inferred from its human counterpart.
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Catalyst Activity

dihydroorotase activity of CAD hexamer [cytosol]

Physical Entity
CAD hexamer [cytosol] (Gallus gallus)
Activity
dihydroorotase activity (GO:0004151)
Inferred From
CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Homo sapiens)
Authored
D'Eustachio, P  (2009-05-01)
Created
D'Eustachio, P  (2009-05-01)
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