Reactome | S1PR2 [plasma membrane]

S1PR2 [plasma membrane]

Stable Identifier

R-GGA-419419

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

S1PR2, A0A3Q2UHB6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Lysosphingolipid and LPA receptors (Gallus gallus)
        
        S1PR2-5 bind S1P (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)
        
        S1PR2-5:S1P [plasma membrane] (Gallus gallus)
        
        S1PR2-5 [plasma membrane] (Gallus gallus)
        
        S1PR2 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A3Q2UHB6

Gene Names

S1PR2

Reference Genes

ENSEMBL:ENSGALG00000049475

ENSEMBL:ENSGALG00010002908.1 S1PR2

Other Identifiers

100857976

GO:0001664

GO:0003376

GO:0004930

GO:0005178

GO:0005737

GO:0005886

GO:0007010

GO:0007165

GO:0007186

GO:0007189

GO:0008528

GO:0010800

GO:0016020

GO:0019222

GO:0023052

GO:0030036

GO:0030154

GO:0036211

GO:0038036

GO:0046847

GO:0048856

GO:0050877

GO:0060079

GO:0060089

GO:0090394

GO:0098794

GO:1903142

GT_Sp_S1PR2_1061

GT_Sp_S1PR2_1062

GT_Sp_S1PR2_1070

Participates

as a member of

S1PR2-5 [plasma membrane] (Gallus gallus)

Inferred From

S1PR2 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000267534

Ensembl

ENSGALT00010006747, ENSGALT00010006744, ENSGALT00010006754, ENSGALT00010006749, ENSGALP00010004108, ENSGALP00010004113, ENSGALP00010004116, ENSGALP00010004111, ENSGALP00010004115, ENSGALP00010004110, ENSGALT00010006752, ENSGALT00010006740, ENSGALG00010002908