Reactome | ADORA1 [plasma membrane]

ADORA1 [plasma membrane]

Stable Identifier

R-GGA-418941

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

ADORA1, P49892

Locations in the PathwayBrowser

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Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR downstream signalling (Gallus gallus)
    - G alpha (i) signalling events (Gallus gallus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
      - The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Nucleotide-like (purinergic) receptors (Gallus gallus)
        
        Adenosine P1 receptors (Gallus gallus)
        
        A1 and A3 receptors bind adenosine (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)
        
        ADORA1,3:Ade-Rib [plasma membrane] (Gallus gallus)
        
        ADORA1,3 [plasma membrane] (Gallus gallus)
        
        ADORA1 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:P49892

Gene Names

ADORA1

Reference Genes

BioGPS Gene:374212 ADORA1

ENSEMBL:ENSGALG00000000168

KEGG Gene (Gallus gallus):374212 ADORA1

Monarch:374212 ADORA1

NCBI Gene:374212 ADORA1

Reference Transcript

RefSeq:NM_204316.3 ADORA1

Participates

as a member of

ADORA1,3 [plasma membrane] (Gallus gallus)

Inferred From

ADORA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_989647.3

OpenTargets

ENSG00000163485

ZINC - Substances

AA1R_CHICK

ZINC - Biogenic

AA1R_CHICK

ZINC target

P49892

PRO

P49892

ZINC - Predictions - Purchasable

AA1R_CHICK