Reactome | phospho-p-Y608,Y614-EPHA7 [plasma membrane]

phospho-p-Y608,Y614-EPHA7 [plasma membrane]

Stable Identifier

R-GGA-3928358

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

plasma membrane

Synonyms

O42422

Locations in the PathwayBrowser

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Developmental Biology (Gallus gallus)

- Nervous system development (Gallus gallus)
  - Axon guidance (Gallus gallus)
    - EPH-Ephrin signaling (Gallus gallus)
      - EPH receptors autophosphorylate (Gallus gallus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
      - EPH-ephrin mediated repulsion of cells (Gallus gallus)
        
        EPHA binds TIAM1 (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        SFKs phosphorylate VAV2,3 (Gallus gallus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        p-EPHs bind VAV2,3 (Gallus gallus)
        
        EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
        
        p-EPH:ephrin oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)
      - EPHA-mediated growth cone collapse (Gallus gallus)
        
        NGEF exchanges GTP for GDP on RHOA (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs:p-Y179-NGEF [plasma membrane] (Gallus gallus)
        
        EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
        
        p-EPHA:EFNA oligomers [plasma membrane] (Gallus gallus)
        
        p-EPHAs:EFNAs [plasma membrane] (Gallus gallus)
        
        p-EPHAs [plasma membrane] (Gallus gallus)
        
        phospho-p-Y608,Y614-EPHA7 [plasma membrane] (Gallus gallus)

External Reference Information

External Reference

UniProt:O42422

Reference Genes

BioGPS Gene:395967

ENSEMBL:ENSGALG00000015593

KEGG Gene (Gallus gallus):395967

Monarch:395967

NCBI Gene:395967

Reference Transcript

RefSeq:NM_205083.1

Participates

as a member of

p-EPHAs [plasma membrane] (Gallus gallus)

Other forms of this molecule

EPHA7 [plasma membrane]

Inferred From

p-Y608,Y614-EPHA7 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 608 (in Homo sapiens)

Coordinate

608

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 614 (in Homo sapiens)

Coordinate

614

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_990414.1

PRO

O42422

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