Reactome | MBL [extracellular region]

MBL [extracellular region]

Stable Identifier

R-GGA-391099

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

extracellular region

Synonyms

SFTPD, Q98TA4

Locations in the PathwayBrowser

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Cell-Cell communication (Gallus gallus)

- Signal regulatory protein family interactions (Gallus gallus)
  - SIRPA binds SFTPA oligomer, SFTPD oligomer (Gallus gallus)
    - SFTPA oligomer, SFTPD oligomer [extracellular region] (Gallus gallus)
      - SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD trimer [extracellular region] (Gallus gallus)
        
        MBL [extracellular region] (Gallus gallus)
    - SIRPA:SFTPA oligomer, SFTPD oligomer [plasma membrane] (Gallus gallus)
      - SFTPA oligomer, SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD trimer [extracellular region] (Gallus gallus)
        
        MBL [extracellular region] (Gallus gallus)

Immune System (Gallus gallus)

- Innate Immune System (Gallus gallus)
  - Toll-like Receptor Cascades (Gallus gallus)
    - Regulation of TLR by endogenous ligand (Gallus gallus)
      - SFTPA/SFTPD binds TLR4:LY96 (Gallus gallus)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD trimer [extracellular region] (Gallus gallus)
        
        MBL [extracellular region] (Gallus gallus)
        
        SP-A/SP-D:TLR4:MD2 [plasma membrane] (Gallus gallus)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD trimer [extracellular region] (Gallus gallus)
        
        MBL [extracellular region] (Gallus gallus)
    - Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
      - Transfer of LPS onto TLR4 (Gallus gallus)
        
        SFTPA oligomer, SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD oligomer [extracellular region] (Gallus gallus)
        
        SFTPD trimer [extracellular region] (Gallus gallus)
        
        MBL [extracellular region] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q98TA4 MBL

Gene Names

MBL

Chain

signal peptide:1-19, chain:20-254

Reference Genes

BioGPS Gene:374267 MBL

ENSEMBL:ENSGALG00000002507 MBL

KEGG Gene (Gallus gallus):374267 MBL

Monarch:374267 MBL

NCBI Gene:374267 MBL

Reference Transcript

RefSeq:NM_204349.2 MBL

Other Identifiers

374267

GO:0001867

GO:0002376

GO:0003674

GO:0005537

GO:0005575

GO:0005576

GO:0005581

GO:0005615

GO:0005622

GO:0005737

GO:0005768

GO:0005771

GO:0005783

GO:0005791

GO:0006810

GO:0006950

GO:0006956

GO:0006958

GO:0008150

GO:0016192

GO:0030246

GO:0031410

GO:0032991

GO:0042592

GO:0043129

GO:0043226

GO:0045087

GO:0050766

GT_A_87_P134178

GT_A_87_P134183

Gga.174.1.S1_at

Participates

as a component of

SFTPD trimer [extracellular region] (Gallus gallus)

Other forms of this molecule

MBL [extracellular region]

MBL [endoplasmic reticulum membrane]

Inferred From

SFTPD [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_989680.2

Ensembl

ENSGALG00000002507, ENSGALP00000040351, ENSGALT00000041145

PRO

Q98TA4