Reactome | AHCTF1 [cytosol]

AHCTF1 [cytosol]

Stable Identifier

R-GGA-376244

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

AHCTF1, A0A8V0Y5R2

Locations in the PathwayBrowser

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Cell Cycle (Gallus gallus)

- Cell Cycle Checkpoints (Gallus gallus)
  - Mitotic Spindle Checkpoint (Gallus gallus)
    - Amplification of signal from the kinetochores (Gallus gallus)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Gallus gallus)
        
        MAD2 associates with the Mad1 kinetochore complex (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Mad1 binds kinetochore (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Release of activated MAD2 from kinetochores (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
- Cell Cycle, Mitotic (Gallus gallus)
  - M Phase (Gallus gallus)
    - Mitotic Metaphase and Anaphase (Gallus gallus)
      - Mitotic Anaphase (Gallus gallus)
        
        Nuclear Envelope (NE) Reassembly (Gallus gallus)
        
        Postmitotic nuclear pore complex (NPC) reformation (Gallus gallus)
        
        AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        POM121 and NDC1 bind the Nup93 complex (Gallus gallus)
        
        Nup93 complex:NUP188:NDC1:POM121:AHCTF1:Chromatin [nuclear envelope] (Gallus gallus)
        
        POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Gallus gallus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Gallus gallus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        POM121 binds the Nup107-Nup160 complex (Gallus gallus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        POM121:Nup107-160 complex:AHCTF1:Chromatin [nuclear envelope] (Gallus gallus)
        
        Nup107-160 complex:AHCTF1:Chromatin [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Separation of Sister Chromatids (Gallus gallus)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Gallus gallus)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
    - Mitotic Prometaphase (Gallus gallus)
      - EML4 and NUDC in mitotic spindle formation (Gallus gallus)
        
        EML4 recruits NUDC to mitotic spindle (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
      - Resolution of Sister Chromatid Cohesion (Gallus gallus)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Gallus gallus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Kinetochore assembly (Gallus gallus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Gallus gallus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Gallus gallus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        AHCTF1 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0Y5R2

Gene Names

AHCTF1

Reference Genes

BioGPS Gene:421484 AHCTF1

ENSEMBL:ENSGALG00010010125.1

Monarch:421484 AHCTF1

NCBI Gene:421484 AHCTF1

UCSC:A0A8V0Y5R2 AHCTF1

Reference Transcript

Other Identifiers

421484

GO:0000776

GO:0000785

GO:0005634

GO:0005635

GO:0005643

GO:0005654

GO:0005737

GO:0016363

GO:0016604

GO:0031080

GO:0031965

GO:0032465

GO:0043226

GO:0051292

GO:0065003

GT_A_87_P058701

GT_A_87_P269478

GT_Xhyb_Chicken_CO762874_4599

Gga.13865.1.S1_s_at

GgaAffx.23279.1.S1_s_at

Participates

as an input of

AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Gallus gallus)

as a component of

Inferred From

AHCTF1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_015139220.2, XP_015139221.2, XP_040553026.1, XP_015139219.2, XP_046794783.1

ENSEMBL

ENSGALG00010010125, ENSGALT00010024056, ENSGALP00010013712

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