Reactome | LOC424111 [cytosol]

LOC424111 [cytosol]

Stable Identifier

R-GGA-376242

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

cytosol

Synonyms

SGOL2, A0A8V0ZUJ2

Locations in the PathwayBrowser

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Cell Cycle (Gallus gallus)

- Cell Cycle Checkpoints (Gallus gallus)
  - Mitotic Spindle Checkpoint (Gallus gallus)
    - Amplification of signal from the kinetochores (Gallus gallus)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Gallus gallus)
        
        MAD2 associates with the Mad1 kinetochore complex (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Mad1 binds kinetochore (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Release of activated MAD2 from kinetochores (Gallus gallus)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Mad1:kinetochore complex [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
- Cell Cycle, Mitotic (Gallus gallus)
  - M Phase (Gallus gallus)
    - Mitotic Metaphase and Anaphase (Gallus gallus)
      - Mitotic Anaphase (Gallus gallus)
        
        Separation of Sister Chromatids (Gallus gallus)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Gallus gallus)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
    - Mitotic Prometaphase (Gallus gallus)
      - EML4 and NUDC in mitotic spindle formation (Gallus gallus)
        
        EML4 recruits NUDC to mitotic spindle (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
      - Resolution of Sister Chromatid Cohesion (Gallus gallus)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Gallus gallus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Kinetochore assembly (Gallus gallus)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Gallus gallus)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Gallus gallus)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Gallus gallus)
        
        Microtubule-bound kinetochore [cytosol] (Gallus gallus)
        
        Kinetochore [cytosol] (Gallus gallus)
        
        LOC424111 [cytosol] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V0ZUJ2

Gene Names

LOC424111

Reference Genes

ENSEMBL:ENSGALG00010022181.1

UCSC:A0A8V0ZUJ2 LOC424111

Other Identifiers

424111

GO:0000775

GO:0000776

GO:0005694

GO:0007059

GO:0043226

GO:0051177

GO:0051301

GT_A_87_P082166

Gga.17257.1.S1_at

GgaAffx.5534.1.S1_at

Participates

as a component of

Kinetochore [cytosol] (Gallus gallus)

Inferred From

SGOL2 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSGALT00010053979, ENSGALG00010022181, ENSGALP00010032514

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