succinate + CoASH + GTP <=> succinylCoA + GDP + Pi

Stable Identifier
R-GGA-373148
Type
Reaction [transition]
Species
Gallus gallus
Compartment
ReviewStatus
5/5
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Mitochondrial succinyl-CoA synthetase catalyzes the reversible reaction of succinate, CoASH, and GTP to form succinylCoA, GDP, and orthophosphate. The enzyme is a heterodimer consisting of an alpha chain and a beta chain that determines whether the reaction involves adenine nucleotides or guanine nucleotides (as here). The biochemical properties of the chicken enzyme have been studied in detail (Hamilton and Ottaway 1981) but the genes encoding its component proteins have not been cloned. The molecular properties of these proteins are inferred from those of their pigeon homologues (Johnson et al. 1998).
Literature References
Participants
Participates
Event Information
Catalyst Activity

succinate-CoA ligase (GDP-forming) activity of succinyl-CoA synthetase dimer, GDP-forming [mitochondrial matrix]

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