fumarate + H2O <=> malate

Stable Identifier
R-GGA-373145
Type
Reaction [transition]
Species
Gallus gallus
Compartment
mitochondrial matrix
ReviewStatus
5/5
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fumarate + H2O <=> malate
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Mitochondrial FH (fumarate hydratase) catalyzes the reversible reaction of fumarate and H2O to form malate. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial FH has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.
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Catalyst Activity

fumarate hydratase activity of FH [mitochondrial matrix]

Physical Entity
FH [mitochondrial matrix] (Gallus gallus)
Activity
fumarate hydratase activity (GO:0004333)
Inferred From
FH tetramer hydrates fumarate to L-malate (Homo sapiens)
Authored
D'Eustachio, P  (2008-09-10)
Created
D'Eustachio, P  (2008-07-14)
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