Formation of Pol zeta complex

Stable Identifier
R-GGA-353434
Type
Reaction [binding]
Species
Gallus gallus
Compartment
ReviewStatus
5/5
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The REV3L and MAD2L2 (REV7) proteins combine to form the Pol zeta complex, an important DNA polymerase taking part in Translesion DNA synthesis (TLS) (Diaz et al. 2001; Nojima et al. 2005; Okada et al. 2005).
Literature References
PubMed ID Title Journal Year
15988022 Multiple roles of vertebrate REV genes in DNA repair and recombination

Kawano, Y, Kohzaki, M, Takeda, S, Yoshimura, M, Saya, H, Okada, T, Sonoda, E

Mol Cell Biol 2005
16357182 Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells

Takahashi, JA, Bishop, DK, Hochegger, H, Saberi, A, Takeda, S, Yoshimura, M, Fukushima, T, Orelli, BJ, Nojima, K, Kikuchi, K, Sonoda, E, Araki, K, Yamazoe, M, Hirano, S, Hashimoto, N, Buerstedde, JM, Takata, M, Arakawa, H, Ohzeki, M, Kawamoto, T, Ishiai, M, Yamamoto, K

Cancer Res 2005
11205333 Evolution and the molecular basis of somatic hypermutation of antigen receptor genes

Flajnik, MF, Diaz, M, Klinman, N

Philos Trans R Soc Lond B Biol Sci 2001
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