Ligation of newly synthesized repair patch to incised DNA in GG-NER

Stable Identifier
R-GGA-353323
Type
Reaction [transition]
Species
Gallus gallus
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

DNA ligase seals the newly synthesized repair patch to the incised DNA restoring the covalent integrity of the repaired strand.

Literature References
PubMed ID Title Journal Year
10197977 Molecular mechanism of nucleotide excision repair

de Laat, WL, Jaspers, NG, Hoeijmakers, JH

Genes Dev. 1999
2234061 Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain

Tanaka, K, Miura, N, Satokata, I, Miyamoto, I, Yoshida, MC, Satoh, Y, Kondo, S, Yasui, A, Okayama, H, Okada, Y

Nature 1990
7565692 Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination

Chen, J, Tomkinson, AE, Ramos, W, Mackey, ZB, Danehower, S, Walter, CA, Schultz, RA, Besterman, JM, Husain, I

Mol. Cell. Biol. 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ligase activity of LIG3 [nucleoplasm]
Physical Entity
Activity
Authored
Reviewed
Created