phosphoenolpyruvate + ADP => pyruvate + ATP

Stable Identifier
R-GGA-353056
Type
Reaction [transition]
Species
Gallus gallus
Compartment
cytosol
Synonyms
Phosphoenolpyruvate and ADP react to form pyruvate + ATP
ReviewStatus
5/5
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phosphoenolpyruvate + ADP => pyruvate + ATP
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Cytosolic pyruvate kinase (PKM2) catalyzes the irreversible reaction of phosphoenolpyruvate and ADP to form pyruvate + ATP. A single entity with pyruvate kinase enzymatic activity has been visualized by starch gel electrophoresis of muscle proteins (Scopes 1968) and cDNA encoding the chicken muscle enzyme has been cloned (Lonberg and Gilbert 1983).

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Catalyst Activity

pyruvate kinase activity of PKM2 [cytosol]

Physical Entity
PKM2 [cytosol] (Gallus gallus)
Activity
pyruvate kinase activity (GO:0004743)
Authored
D'Eustachio, P  (2008-09-10)
Reviewed
Harris, RA  (2008-09-10)
Created
D'Eustachio, P  (2008-06-10)
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