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MADH2 [cytosol]
Stable Identifier
R-GGA-3006353-2
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
SMAD2, Q8UWF3
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Gallus gallus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Gallus gallus)
Dephosphorylated SMAD2/3 translocates to the cytosol (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Ub-specific processing proteases (Gallus gallus)
USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Gallus gallus)
USP15:SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Gallus gallus)
SMAD1,SMAD2,SMAD3,KEAP1,SMAD7:SMURF2:TGFBR1 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by TGFB family members (Gallus gallus)
Signaling by Activin (Gallus gallus)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
Activated type I receptor phosphorylates SMAD2/3 directly (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
TGFB1:p-TGFBR:ZFYVE9:SMAD2/3 [early endosome membrane] (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
Downregulation of TGF-beta receptor signaling (Gallus gallus)
Degradation of ubiquitinated SMAD2 (Gallus gallus)
Ub-SMAD2 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
MTMR4 dephosphorylates SMAD2/3 (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
PMEPA1 sequesters unphosphorylated SMAD2/3 (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
SMAD2/3:PMEPA1 [plasma membrane] (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
SMURF2 binds SMAD2 (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
SMAD2:SMURF2 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
SMURF2 ubiquitinates SMAD2 (Gallus gallus)
SMAD2:SMURF2 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
Ub-SMAD2 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Gallus gallus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Gallus gallus)
Dephosphorylated SMAD2/3 translocates to the cytosol (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Gallus gallus)
SMAD2,3 [cytosol] (Gallus gallus)
Homologues of SMAD2 [cytosol] (Gallus gallus)
MADH2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q8UWF3
Gene Names
MADH2
Reference Genes
BioGPS Gene:395247 MADH2
ENSEMBL:ENSGALG00000036001
KEGG Gene (Gallus gallus):395247 MADH2
Monarch:395247 MADH2
NCBI Gene:395247 MADH2
Reference Transcript
RefSeq:NM_204561.1 MADH2
Participates
as a member of
Homologues of SMAD2 [cytosol] (Gallus gallus)
Other forms of this molecule
MADH2 [cytosol]
phospho-MADH2 [cytosol]
MADH2 [nucleoplasm]
phospho-MADH2 [cytosol]
phospho-MADH2 [nucleoplasm]
Inferred From
SMAD2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_989892.1
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