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GSK3B [cytosol]
Stable Identifier
R-GGA-2997551
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
A0A3Q2TVV5
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to heat stress (Gallus gallus)
Regulation of HSF1-mediated heat shock response (Gallus gallus)
Constitutive phosphorylation by GSK3 (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
Semaphorin interactions (Gallus gallus)
CRMPs in Sema3A signaling (Gallus gallus)
Phosphorylation of CRMPs by GSK3beta (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog 'off' state (Gallus gallus)
GLI3 is processed to GLI3R by the proteasome (Gallus gallus)
GSK3 phosphorylates p-GLI3 (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Signaling by WNT (Gallus gallus)
Degradation of beta-catenin by the destruction complex (Gallus gallus)
AXIN is phosphorylated in the destruction complex (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Association of beta-catenin with the destruction complex (Gallus gallus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Beta-catenin phosphorylation cascade (Gallus gallus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Gallus gallus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Gallus gallus)
FRAT1,2:GSK3beta [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Gallus gallus)
FRAT1,2:GSK3beta [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Gallus gallus)
FRAT1,2:GSK3beta [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Degradation of ubiquitinated beta catenin by the proteasome (Gallus gallus)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Gallus gallus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Phosphorylation of APC component of the destruction complex (Gallus gallus)
CK1alpha (GSK3) [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Gallus gallus)
DVL recruits GSK3beta:AXIN1 to the receptor complex (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
FRAT proteins bind GSK3beta (Gallus gallus)
FRAT1,2:GSK3beta [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Gallus gallus)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [early endosome membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
GSK3B [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A3Q2TVV5
Reference Genes
ENSEMBL:ENSGALG00000014977
Participates
as a component of
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
FRAT1,2:GSK3beta [cytosol] (Gallus gallus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Gallus gallus)
GSK3B:AXIN1 [cytosol] (Gallus gallus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Gallus gallus)
as a candidate of
CK1alpha (GSK3) [cytosol] (Gallus gallus)
as an input of
FRAT proteins bind GSK3beta (Gallus gallus)
Other forms of this molecule
GSK3B [nucleoplasm]
Inferred From
GSK3B [cytosol]
(Homo sapiens)
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