AGRN binds NCAM1, PTPRS

Stable Identifier
R-GGA-2467642
Type
Reaction [binding]
Species
Gallus gallus
Compartment
General
SVG |   | PPTX  | SBGN
AGRN binds NCAM1, PTPRS

Several agrin (AGRN) ligands require the presence of its heparan-sulfate sidechains and probably represent interactions with them. Membrane-associated ligands include the neural cell adhesion molecule NCAM1 (Burg et al. 1995, Tsen et al. 1995, Cole & Halfter 1996 - see REACT_19071) and PTPRS (receptor protein tyrosine phosphatase sigma) (Aricescu et al. 2002).

Literature References
PubMed ID Title Journal Year
7674377 Analysis of proteoglycan expression in developing chicken brain: characterization of a heparan sulfate proteoglycan that interacts with the neural cell adhesion molecule

Burg, MA, Halfter, W, Cole, GJ

J. Neurosci. Res. 1995
11865065 Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase sigma

Aricescu, AR, McKinnell, IW, Halfter, W, Stoker, AW

Mol. Cell. Biol. 2002
Participants
Orthologous Events
Authored
Reviewed
Created
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