Reactome | RAD51C [nucleoplasm]

RAD51C [nucleoplasm]

Stable Identifier

R-GGA-217039

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

nucleoplasm

Synonyms

RAD51C, A0A1D5P635

Locations in the PathwayBrowser

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DNA Repair (Gallus gallus)

- DNA Double-Strand Break Repair (Gallus gallus)
  - Homology Directed Repair (Gallus gallus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Gallus gallus)
      - HDR through Homologous Recombination (HRR) (Gallus gallus)
        
        D-loop extension by DNA polymerases (Gallus gallus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Homologous DNA Pairing and Strand Exchange (Gallus gallus)
        
        CX3 complex binds D-loop structures (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        CX3 complex formation (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        D-loop formation mediated by PALB2, BRCA2 and RAD51 (Gallus gallus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Presynaptic phase of homologous DNA pairing and strand exchange (Gallus gallus)
        
        BCDX2 complex formation (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex stabilizes RAD51 filament (Gallus gallus)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Resolution of D-Loop Structures (Gallus gallus)
        
        Resolution of D-loop Structures through Holliday Junction Intermediates (Gallus gallus)
        
        Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Gallus gallus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Ligation of DNA and formation of Holliday structures following repair synthesis (Gallus gallus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Gallus gallus)
        
        CX3 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)
        
        Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Gallus gallus)
        
        BCDX2 complex [nucleoplasm] (Gallus gallus)
        
        RAD51C [nucleoplasm] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A1D5P635

Gene Names

RAD51C

Reference Genes

ENSEMBL:ENSGALG00000040380

ENSEMBL:ENSGALG00010029783.1 RAD51C

Other Identifiers

417626

GO:0000400

GO:0000707

GO:0003677

GO:0003824

GO:0005524

GO:0005634

GO:0005657

GO:0005694

GO:0006281

GO:0006310

GO:0007131

GO:0008821

GO:0016787

GO:0022414

GO:0033063

GO:0033065

GO:0043226

GO:0065003

GO:0140013

GO:0140097

GO:0140299

GO:0140657

GO:0140664

GgaAffx.3166.1.S1_at

Participates

as an input of

as a component of

Inferred From

RAD51C [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000108384

Ensembl

ENSGALP00010044744, ENSGALG00010029783, ENSGALT00010072054

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