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DNA-PKcs, DNA-dependent protein kinase catalytic subunit [nucleoplasm]
Stable Identifier
R-GGA-217031
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
DNA-PK catalytic subunit, PRKDC/XRCC7
Locations in the PathwayBrowser
Expand all
DNA replication and repair (Gallus gallus)
DNA repair (Gallus gallus)
Double strand break repair (Gallus gallus)
Homologous recombination repair (Gallus gallus)
Homologous recombination repair (HRR) of replication-independent double-strand breaks (Gallus gallus)
ATM mediated response to DNA double-strand break (Gallus gallus)
ATM mediated phosphorylation of repair proteins (Gallus gallus)
Phosphorylation of H2AX at S139 by ATM at the site of DSB (Gallus gallus)
PI3-kinase family [nucleoplasm] (Gallus gallus)
DNA-PKcs, DNA-dependent protein kinase catalytic subunit [nucleoplasm] (Gallus gallus)
Non-homologous end joining (NHEJ) (Gallus gallus)
Autophosphorylation of DNA-PKcs (Gallus gallus)
DNA-PKcs, DNA-dependent protein kinase catalytic subunit [nucleoplasm] (Gallus gallus)
Removal of repair proteins and ligation of the processed ends of the DNA double-strand break (Gallus gallus)
DNA-PKcs, DNA-dependent protein kinase catalytic subunit [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q8QGX4 PRKDC
Gene Names
PRKDC, XRCC7
Chain
chain:1-4134
Reference Genes
BioGPS Gene:395376 PRKDC
KEGG Gene (Gallus gallus):395376 PRKDC
Monarch:395376 PRKDC
NCBI Gene:395376 PRKDC
Reference Transcript
RefSeq:NM_204658.2 PRKDC
Participates
as an output of
Removal of repair proteins and ligation of the processed ends of the DNA double-strand break (Gallus gallus)
as an input of
Autophosphorylation of DNA-PKcs (Gallus gallus)
as a member of
PI3-kinase family [nucleoplasm] (Gallus gallus)
Other forms of this molecule
Phospho-DNA-PKcs [nucleoplasm]
Cross References
RefSeq
NP_989989.2
OpenTargets
ENSG00000253729
IntEnz
2.7.11.1
PRO
Q8QGX4
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