Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
STT3 [nucleoplasm]
Stable Identifier
R-GGA-217006
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Synonyms
CHEK1, Serine/threonine-protein kinase Chk1
Locations in the PathwayBrowser
Expand all
DNA replication and repair (Gallus gallus)
DNA repair (Gallus gallus)
Chk1-controlled and DNA-damage induced centrosome duplication (Gallus gallus)
Phosphorylation of Chk1 by ATM upon DNA damage (Gallus gallus)
STT3 [nucleoplasm] (Gallus gallus)
Phosphorylation of Chk1 by ATR (Gallus gallus)
STT3 [nucleoplasm] (Gallus gallus)
Double strand break repair (Gallus gallus)
Homologous recombination repair (Gallus gallus)
Homologous recombination repair (HRR) of replication-independent double-strand breaks (Gallus gallus)
ATM mediated response to DNA double-strand break (Gallus gallus)
ATM mediated phosphorylation of repair proteins (Gallus gallus)
Phosphorylation of Chk1 by ATM upon DNA damage (Gallus gallus)
STT3 [nucleoplasm] (Gallus gallus)
Homologous recombination repair of replication-dependent double-strand breaks (Gallus gallus)
Activation of ATR by interaction with RAD9-TopBP1 complex (Gallus gallus)
ATRIP-ATR complex [nucleoplasm] (Gallus gallus)
STT3 [nucleoplasm] (Gallus gallus)
TopBP1 association with ATR via its activation domain (AD) [nucleoplasm] (Gallus gallus)
ATRIP-ATR complex [nucleoplasm] (Gallus gallus)
STT3 [nucleoplasm] (Gallus gallus)
Phosphorylation of Chk1 by ATR (Gallus gallus)
STT3 [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q8AYC9 CHEK1
Gene Names
CHEK1, CHK1
Chain
chain:1-476
Reference Genes
BioGPS Gene:374260 CHEK1
ENSEMBL:ENSGALG00010023828.1 CHEK1
ENSEMBL:ENSGALG00015012450 CHEK1
KEGG Gene (Gallus gallus):374260 CHEK1
Monarch:374260 CHEK1
NCBI Gene:374260 CHEK1
Reference Transcript
RefSeq:NM_204345.1 CHEK1
Other Identifiers
374260
EC 2.7.11.1
GO:0000077
GO:0000166
GO:0000228
GO:0000278
GO:0000785
GO:0000794
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0006281
GO:0006310
GO:0006325
GO:0006338
GO:0006468
GO:0006974
GO:0007010
GO:0007049
GO:0007095
GO:0010569
GO:0016301
GO:0016310
GO:0016740
GO:0018107
GO:0023052
GO:0035402
GO:0035556
GO:0036211
GO:0042770
GO:0043226
GO:0045814
GO:0045839
GO:0046602
GO:0106310
GO:0140014
GO:0140096
GT_A_87_P016242
GT_A_87_P064741
Gga.11916.1.S1_at
Gga.4288.1.S1_at
Participates
as a component of
ATRIP-ATR complex [nucleoplasm] (Gallus gallus)
as an input of
Phosphorylation of Chk1 by ATR (Gallus gallus)
Phosphorylation of Chk1 by ATM upon DNA damage (Gallus gallus)
Other forms of this molecule
phospho-STT3 [nucleoplasm]
Cross References
RefSeq
NP_989676.1
OpenTargets
ENSG00000149554
Ensembl
ENSGALT00010058076
,
ENSGALP00010035254
,
ENSGALG00010023828
PRO
Q8AYC9
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text