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NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm]
Stable Identifier
R-GGA-216923
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA replication and repair (Gallus gallus)
DNA repair (Gallus gallus)
Chk1-controlled and DNA-damage induced centrosome duplication (Gallus gallus)
Activation and association of ATM kinase at the DNA damage sites (Gallus gallus)
MRE11-RAD50-NBS1 complex [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
Association of MRE11 and NBS1 leads to nuclear localization of MRN complex (Gallus gallus)
MRE11-RAD50-NBS1 complex [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
Double strand break repair (Gallus gallus)
Homologous recombination repair (Gallus gallus)
Homologous recombination repair (HRR) of replication-independent double-strand breaks (Gallus gallus)
ATM mediated response to DNA double-strand break (Gallus gallus)
ATM mediated phosphorylation of repair proteins (Gallus gallus)
Phosphorylation of NBS1 by ATM (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
Activation and association of ATM kinase at the DNA damage sites (Gallus gallus)
MRE11-RAD50-NBS1 complex [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
Recruitment of repair and signaling proteins to double-strand breaks (Gallus gallus)
Association of MRE11 and NBS1 leads to nuclear localization of MRN complex (Gallus gallus)
MRE11-RAD50-NBS1 complex [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
NBS, Nijmegen breakage syndrome protein 1 homolog [nucleoplasm] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q9DE07 NBN
Gene Names
NBN, NBS1
Chain
chain:1-753
Reference Genes
BioGPS Gene:374246 NBN
KEGG Gene (Gallus gallus):374246 NBN
Monarch:374246 NBN
NCBI Gene:374246 NBN
Reference Transcript
RefSeq:NM_204337.1 NBN
Participates
as an input of
Phosphorylation of NBS1 by ATM (Gallus gallus)
Association of MRE11 and NBS1 leads to nuclear localization of MRN complex (Gallus gallus)
as a component of
MRE11-RAD50-NBS1 complex [nucleoplasm] (Gallus gallus)
This entity regulates
Positively
Activation and association of ATM kinase at the DNA damage sites
(Gallus gallus)
Other forms of this molecule
phospho-NBS1 [nucleoplasm]
Cross References
RefSeq
NP_989668.1
OpenTargets
ENSG00000104320
PRO
Q9DE07
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