C5b:C6:C7 inserts into the target cell membrane

Stable Identifier
R-GGA-2132133
Type
Reaction [transition]
Species
Gallus gallus
Compartment
extracellular region, plasma membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
C5b:C6:C7 inserts into the target cell membrane
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Upon binding of C7 to C5b:C6, the trimolecular C5b:C6:C7 complex undergoes a conformational transition that allows insertion of this complex into the lipid bilayer of the target cell membrane.
Literature References
Participants
Input
Output
Participates
as an event of
This event is regulated
Negatively by
Regulator
VTN:C5b:C6:C7 [extracellular region] (Gallus gallus)
Inferred From
C7 binds C5b:C6 (Homo sapiens)
Authored
Shamovsky, V  (2012-12-20)
Reviewed
D'Eustachio, P  (2012-11-07)
Jupe, S  (2013-01-31)
Created
Shamovsky, V  (2012-02-21)
Cite Us!