Vitronectin prevents C9 polymerization

Stable Identifier
R-GGA-2132088
Type
Reaction [binding]
Species
Gallus gallus
Compartment
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Vitronectin blocks MAC complex formation by inhibiting C9 polymerization.

Vitronectin transcripts were detected in the brain, liver and spleen of adult chickens. The polypeptide sequence of chicken vitronectin exhibits 57% identity with human ortholog. Chicken events involving vitronectin have not been verified experimentally but are inferred from properties of the orthologous human proteins.

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