Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
Search ...
Go!
Src family tyrosine kinases (SFKs) [cytosol]
Stable Identifier
R-GGA-211064
Type
Set [DefinedSet]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
Phosphorylation of CD28 (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
CTLA4 inhibitory signaling (Gallus gallus)
Phosphorylation of CTLA-4 (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SHP2 phosphatase binds CTLA-4 (Gallus gallus)
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Gallus gallus)
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by SCF-KIT (Gallus gallus)
Dimerization of STATs (Gallus gallus)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Disassociation and translocation of STATs to the nucleus (Gallus gallus)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
GRB2 is indirectly recruited to p-KIT through SHP2 (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Gallus gallus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
JAK2 binds to p-KIT (Gallus gallus)
JAK2:SFKS:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of GAB2 by SFKs (Gallus gallus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of JAK2 (Gallus gallus)
JAK2:SFKS:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of SHP2 by SFKs (Gallus gallus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of STATs (Gallus gallus)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of p-KIT on Y900 by Src kinases (Gallus gallus)
SFKs:p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Recruitment of STATs (Gallus gallus)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Regulation of KIT signaling (Gallus gallus)
Interaction of APS and p-KIT (Gallus gallus)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of APS (Gallus gallus)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-APS dimer:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Recruitment of CBL to KIT (Gallus gallus)
CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane] (Gallus gallus)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Gallus gallus)
p-APS dimer:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Gallus gallus)
p-APS dimer:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SHP2 interacts with p-KIT (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Synthesis of PIP3 from PIP2 by PI3K (Gallus gallus)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Participants
members
FYN [cytosol] (Gallus gallus)
LYN [cytosol] (Gallus gallus)
YES1 [cytosol] (Gallus gallus)
Homologues of SRC-2 [cytosol] (Gallus gallus)
LCK [cytosol] (Gallus gallus)
Participant Of
input
Phosphorylation of CTLA-4
hasComponent
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane]
SFKs:p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane]
SFKs:p-KIT complex [plasma membrane]
Inferred From
Src family tyrosine kinases (SFKs) [cytosol] (Homo sapiens)
© 2019
Reactome
