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Src family tyrosine kinases (SFKs) [cytosol]
Stable Identifier
R-GGA-211064
Type
Set [DefinedSet]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Gallus gallus)
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPH-ephrin mediated repulsion of cells (Gallus gallus)
EPHA binds TIAM1 (Gallus gallus)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Gallus gallus)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
SFKs phosphorylate VAV2,3 (Gallus gallus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Gallus gallus)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Gallus gallus)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
EFNAs:p-EPHAs:SFKs:TIAM1 [plasma membrane] (Gallus gallus)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
VAV exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Gallus gallus)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-EPHs bind VAV2,3 (Gallus gallus)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Gallus gallus)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EPHA-mediated growth cone collapse (Gallus gallus)
NGEF exchanges GTP for GDP on RHOA (Gallus gallus)
EFNAs:p-EPHAs:SFKs:p-Y179-NGEF [plasma membrane] (Gallus gallus)
EFNAs:p-EPHAs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EPHB-mediated forward signaling (Gallus gallus)
EPHB phosphorylates TIAM1 (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EPHB:NMDAR binds TIAM1 (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:p-Y829-TIAM1 [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] (Gallus gallus)
EFNBs:p-EPHBs:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Hemostasis (Gallus gallus)
Cell surface interactions at the vascular wall (Gallus gallus)
PECAM1 interactions (Gallus gallus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CTLA4 inhibitory signaling (Gallus gallus)
SHP2 phosphatase binds CTLA-4 (Gallus gallus)
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Gallus gallus)
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by SCF-KIT (Gallus gallus)
GRB2 is indirectly recruited to p-KIT through SHP2 (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Indirect recruitment of GAB2 to p-KIT (Gallus gallus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Gallus gallus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of GAB2 by SFKs (Gallus gallus)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Phosphorylation of SHP2 by SFKs (Gallus gallus)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Synthesis of PIP3 from PIP2 by PI3K (Gallus gallus)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
p-SHP2:p-KIT complex [plasma membrane] (Gallus gallus)
SFKs:p-KIT complex [plasma membrane] (Gallus gallus)
Src family tyrosine kinases (SFKs) [cytosol] (Gallus gallus)
Participants
members
LYN [cytosol] (Gallus gallus)
YES1 [cytosol] (Gallus gallus)
SRC-2 [cytosol] (Gallus gallus)
Participant Of
hasComponent
EFNAs:p-EPHAs:SFKs [plasma membrane]
EFNBs:p-EPHBs:SFKs [plasma membrane]
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane]
p-Y165,Y182-CTLA-4 dimer:SFKs [plasma membrane]
SFKs:p-KIT complex [plasma membrane]
Inferred From
Src family tyrosine kinases (SFKs) [cytosol] (Homo sapiens)
SRC,FYN,YES,LYN [cytosol] (Homo sapiens)
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