Reactome | NCAN [lysosomal lumen]

NCAN [lysosomal lumen]

Stable Identifier

R-GGA-2065109

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

lysosomal lumen

Synonyms

C6S-NCAN, A0A8V1AG58

Locations in the PathwayBrowser

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Metabolism (Gallus gallus)

- Metabolism of carbohydrates and carbohydrate derivatives (Gallus gallus)
  - Glycosaminoglycan metabolism (Gallus gallus)
    - Chondroitin sulfate/dermatan sulfate metabolism (Gallus gallus)
      - CS/DS degradation (Gallus gallus)
        
        DSPG and CSPG translocate to the lysosome for degradation (Gallus gallus)
        
        CSPGs,DSPGs [lysosomal lumen] (Gallus gallus)
        
        CSPGs [lysosomal lumen] (Gallus gallus)
        
        C6S-PG [lysosomal lumen] (Gallus gallus)
        
        NCAN [lysosomal lumen] (Gallus gallus)

External Reference Information

External Reference

UniProt:A0A8V1AG58

Gene Names

NCAN

Reference Genes

BioGPS Gene:395493 NCAN

ENSEMBL:ENSGALG00010028386.1

Monarch:395493 NCAN

NCBI Gene:395493 NCAN

UCSC:A0A8V1AG58 NCAN

Reference Transcript

RefSeq:NM_204740.2 NCAN

Other Identifiers

395493

GO:0001501

GO:0005509

GO:0005540

GO:0005576

GO:0005615

GO:0007155

GO:0007417

GO:0030246

GO:0030312

GO:0031012

GO:0045202

GO:0048856

GO:0072534

GT_A_87_P037882

Gga.1517.1.S1_at

Participates

as a member of

C6S-PG [lysosomal lumen] (Gallus gallus)

Other forms of this molecule

NCAN [Golgi lumen]

NCAN [extracellular region]

NCAN [lysosomal lumen]

NCAN [extracellular region]

NCAN [lysosomal lumen]

NCAN [Golgi lumen]

Inferred From

C6S-NCAN [lysosomal lumen] (Homo sapiens)

Modified Residues

Name

O-xylosyl-L-serine (ChEBI:63512) at unknown position

Modification

beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc6S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group

PsiMod Name

O-xylosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O3-xylosylserine.

Cross References

RefSeq

NP_990071.2

ENSEMBL

ENSGALG00010028386, ENSGALT00010068777, ENSGALP00010042242

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