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LRP6 [plasma membrane]
Stable Identifier
R-GGA-206252
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
A0A1D5PJP6
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by WNT (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Gallus gallus)
DVL recruits GSK3beta:AXIN1 to the receptor complex (Gallus gallus)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Gallus gallus)
SOST binds LRP5/6 (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
SOST:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
Regulation of FZD by ubiquitination (Gallus gallus)
USP8 deubiquitinates FZD to potentiate WNT signaling (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
ZNRF3 ubiquitinates FZD to promote its downregulation (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
LRP6 [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5PJP6
Reference Genes
ENSEMBL:ENSGALG00000031503
Participates
as an input of
SOST binds LRP5/6 (Gallus gallus)
as a component of
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6 [plasma membrane] (Gallus gallus)
SOST:LRP5/6 [plasma membrane] (Gallus gallus)
WNT:FZD:LRP5/6 [plasma membrane] (Gallus gallus)
Other forms of this molecule
phospho-p-LRP6 [early endosome membrane]
phospho-p-2S,S1490,2T-LRP6 [plasma membrane]
phospho-p-4S,3T,T1479,S1490,T1493-LRP6 [plasma membrane]
Inferred From
LRP5/6 [plasma membrane]
(Homo sapiens)
LRP6 [plasma membrane]
(Homo sapiens)
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