Reactome | phospho-PRLR [endosome lumen]

phospho-PRLR [endosome lumen]

Stable Identifier

R-GGA-2002376

Type

Protein [EntityWithAccessionedSequence]

Species

Gallus gallus

Compartment

endosome lumen

Synonyms

p-Y611-PRLR, Q6QDA0

Locations in the PathwayBrowser

Expand all

Immune System (Gallus gallus)

- Cytokine Signaling in Immune system (Gallus gallus)
  - Prolactin receptor signaling (Gallus gallus)
    - Prolactin receptor is internalized (Gallus gallus)
      - PRLR ligands:p-S349- PRLR:JAK2 dimer [endosome lumen] (Gallus gallus)
        
        2xp-S349-PRLR:2xJAK2 [endosome lumen] (Gallus gallus)
        
        p-S349-PRLR:JAK2 [endosome lumen] (Gallus gallus)
        
        phospho-PRLR [endosome lumen] (Gallus gallus)

External Reference Information

External Reference

UniProt:Q6QDA0

Gene Names

PRLR

Reference Genes

BioGPS Gene:395660 PRLR

ENSEMBL:ENSGALG00000003446

Monarch:395660 PRLR

NCBI Gene:395660 PRLR

Reference Transcript

Participates

as a component of

p-S349-PRLR:JAK2 [endosome lumen] (Gallus gallus)

Other forms of this molecule

PRLR [plasma membrane]

phospho-PRLR [plasma membrane]

Inferred From

p-Y611-PRLR [endosome lumen] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 611 (in Homo sapiens)

Coordinate

611

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_015132722.1, XP_015132724.1, XP_015132723.1, XP_015132726.1

OpenTargets

ENSG00000113494

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