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NFKB1(1-433):RELA [cytosol]
Stable Identifier
R-GGA-194043
Type
Complex
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to mechanical stimuli (Gallus gallus)
Response of endothelial cells to shear stress (Gallus gallus)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Gallus gallus)
PTK2 (FAK) and Gq/11 enhance the degradation of NFKBIA (IkBalpha), phosphorylation of RELA (p65) on serine-536, and translocation of p-S536-RELA:NFKB1 (p65:p50) to the nucleus (Gallus gallus)
IkB(alpha):NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Downstream signaling events of B Cell Receptor (BCR) (Gallus gallus)
Activation of NF-kappaB in B cells (Gallus gallus)
NF-kappaB translocates from the cytosol to the nucleus (Gallus gallus)
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Gallus gallus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:p-IKB [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Gallus gallus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:p-IKB [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
SCF-beta-TrCP ubiquitinylates IkB (Gallus gallus)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Gallus gallus)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:p-IKB [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Ubiquitinated IkB is degraded (Gallus gallus)
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
TCR signaling (Gallus gallus)
Downstream TCR signaling (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1:RELA translocates from the cytosol to the nucleus (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-1 family signaling (Gallus gallus)
Interleukin-1 signaling (Gallus gallus)
NFKB1:RELA translocates from the cytosol to the nucleus (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
C-type lectin receptors (CLRs) (Gallus gallus)
CLEC7A (Dectin-1) signaling (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1:RELA translocates from the cytosol to the nucleus (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated NF-kB activation (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1:RELA translocates from the cytosol to the nucleus (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
p75 NTR receptor-mediated signalling (Gallus gallus)
Regulated proteolysis of p75NTR (Gallus gallus)
p75NTR ICD signals to NF-kB (Gallus gallus)
NF-kB:p75NTR ICD:TRAF6 [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
p75NTR signals via NF-kB (Gallus gallus)
NF-kB is activated and signals survival (Gallus gallus)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Gallus gallus)
IkB(alpha):NF-kB complex [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
NF-kB migrates to the nucleus and turns on transcription (Gallus gallus)
NFKB1(1-433):RELA [cytosol] (Gallus gallus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
NFKB1 [cytosol]
(Gallus gallus)
RELA [cytosol]
(Gallus gallus)
Participates
as an output of
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Gallus gallus)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Gallus gallus)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Gallus gallus)
as a component of
NF-kappaB p50:p65:IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:p-IKB [cytosol] (Gallus gallus)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Gallus gallus)
NF-kB:p75NTR ICD:TRAF6 [cytosol] (Gallus gallus)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Gallus gallus)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Gallus gallus)
IkB(alpha):NF-kB complex [cytosol] (Gallus gallus)
as a member of
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Gallus gallus)
as an input of
NF-kB migrates to the nucleus and turns on transcription (Gallus gallus)
p75NTR ICD signals to NF-kB (Gallus gallus)
NFKB1:RELA translocates from the cytosol to the nucleus (Gallus gallus)
Inferred From
NFKB1(1-433):RELA [cytosol]
(Homo sapiens)
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