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phospho-p-Y55-SPRY2 [cytosol]
Stable Identifier
R-GGA-182950
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
F1NZG9
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by EGFR (Gallus gallus)
EGFR downregulation (Gallus gallus)
CBL binds and ubiquitinates phosphorylated Sprouty (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Gallus gallus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
phospho-p-Y55-SPRY2 [cytosol] (Gallus gallus)
CBL ubiquitinates Sprouty (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Gallus gallus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
phospho-p-Y55-SPRY2 [cytosol] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Gallus gallus)
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
phospho-p-Y55-SPRY2 [cytosol] (Gallus gallus)
Sprouty lures CBL away from EGFR (Gallus gallus)
phospho-p-Y55-SPRY2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:F1NZG9
Reference Genes
ENSEMBL:ENSGALG00000016906
UCSC:F1NZG9
Participates
as a member of
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
as an input of
Sprouty lures CBL away from EGFR (Gallus gallus)
Other forms of this molecule
phospho-p-S111,S120-SPRY2 [cytosol]
phospho-p-Y55,Y227-SPRY2 [plasma membrane]
SPRY2 [plasma membrane]
SPRY2 [cytosol]
Inferred From
p-Y55-SPRY2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 55 (in Homo sapiens)
Coordinate
55
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
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