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phospho-SPRY1 [cytosol]
Stable Identifier
R-GGA-182933
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
p-Y53-SPRY1, A4LA71
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by EGFR (Gallus gallus)
EGFR downregulation (Gallus gallus)
CBL binds and ubiquitinates phosphorylated Sprouty (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Gallus gallus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
phospho-SPRY1 [cytosol] (Gallus gallus)
CBL ubiquitinates Sprouty (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:CBL:Ub-p-Y53/55-SPRY1/2 [plasma membrane] (Gallus gallus)
Ub-p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
phospho-SPRY1 [cytosol] (Gallus gallus)
EGF-like ligands:p-6Y-EGFR:CBL:p-Y53/55-SPRY1/2 [plasma membrane] (Gallus gallus)
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
phospho-SPRY1 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A4LA71
Gene Names
SPRY1
Reference Genes
BioGPS Gene:395583 SPRY1
ENSEMBL:ENSGALG00000042067
KEGG Gene (Gallus gallus):395583 SPRY1
Monarch:395583 SPRY1
NCBI Gene:395583 SPRY1
Reference Transcript
RefSeq:NM_001097524.1 SPRY1
RefSeq:XM_015276128.1 SPRY1
RefSeq:XM_015276127.1 SPRY1
Participates
as a member of
p-Y53/55-SPRY1/2 [cytosol] (Gallus gallus)
Other forms of this molecule
SPRY1 [cytosol]
SPRY1 [plasma membrane]
Inferred From
p-Y53-SPRY1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 53 (in Homo sapiens)
Coordinate
53
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
XP_015131613.1
,
NP_001090993.1
,
XP_015131614.1
OpenTargets
ENSG00000164056
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