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MAP2K4 [cytosol]
Stable Identifier
R-GGA-168107
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
MAP2K4, A0A1D5NVP0
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-17 signaling (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
FCERI mediated MAPK activation (Gallus gallus)
Phosphorylation of MEK4 by MEKK1 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 10 (TLR10) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor 2 (TLR2) Cascade (Gallus gallus)
Toll Like Receptor TLR1:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor TLR6:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor 3 (TLR3) Cascade (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor 5 (TLR5) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
Toll Like Receptor 9 (TLR9) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
MAP2K4 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A1D5NVP0
Gene Names
MAP2K4
Reference Genes
BioGPS Gene:417312 MAP2K4
ENSEMBL:ENSGALG00000032178
ENSEMBL:ENSGALG00010029573.1 MAP2K4
Monarch:417312 MAP2K4
NCBI Gene:417312 MAP2K4
Reference Transcript
RefSeq:XM_015295238.1 MAP2K4
Other Identifiers
417312
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0006468
GO:0007254
GO:0008545
GO:0016740
GO:0023052
GO:0036211
GO:0140096
GT_A_87_P067001
GgaAffx.644.1.S1_at
GgaAffx.644.2.S1_s_at
Participates
as an input of
Phosphorylation of MEK4 by MEKK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
Other forms of this molecule
phospho-MAP2K4 [cytosol]
Inferred From
MAP2K7,MAP2K4 [cytosol]
(Homo sapiens)
MAP2K4 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_015150724.1
OpenTargets
ENSG00000065559
Ensembl
ENSGALT00010071479
,
ENSGALG00010029573
,
ENSGALP00010044169
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