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B2M [plasma membrane]
Stable Identifier
R-GGA-167743
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
plasma membrane
Synonyms
B2M(21-119), P21611
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Gallus gallus)
Expression of peptide bound class I MHC on cell surface (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Antigen processing-Cross presentation (Gallus gallus)
ER-Phagosome pathway (Gallus gallus)
Export of peptide loaded MHC class I complex to PM (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Endosomal/Vacuolar pathway (Gallus gallus)
Translocation of peptide bound MHC class I complex to cell surface (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Gallus gallus)
KLRC1:KLRD1 heterodimer interacts with HLA-E (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
HLA-E interacting with KLRC1:KLRD1 [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
TCR binds microbial lipid-based antigen via CD1 (Gallus gallus)
CD1:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1A:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1A:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1B:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1C:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1D:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1D:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1:B2M:microbial lipid:TCR [plasma membrane] (Gallus gallus)
CD1:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1A:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1A:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1B:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1C:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1D:B2M:microbial lipid [plasma membrane] (Gallus gallus)
CD1D:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
TCR binds self-lipid-based antigen via CD1 (Gallus gallus)
CD1:B2M:self-lipid [plasma membrane] (Gallus gallus)
CD1A:B2M:self-lipid [plasma membrane] (Gallus gallus)
CD1A:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1B:B2M:self lipid [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1D:B2M:sel-lipid [plasma membrane] (Gallus gallus)
CD1D:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1:B2M:self-lipid:TCR [plasma membrane] (Gallus gallus)
CD1:B2M:self-lipid [plasma membrane] (Gallus gallus)
CD1A:B2M:self-lipid [plasma membrane] (Gallus gallus)
CD1A:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1B:B2M:self lipid [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
CD1D:B2M:sel-lipid [plasma membrane] (Gallus gallus)
CD1D:B2M [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
TCR complex interacts with peptide antigen-presenting MHC Class I (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Gallus gallus)
Antigen peptide bound class I MHC [plasma membrane] (Gallus gallus)
Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Innate Immune System (Gallus gallus)
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Phosphorylation and activation of VAV2/VAV3 by SYK (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Phosphorylation of BTK by p-SYK (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)
p-SYK/p-BTK [plasma membrane] (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Phosphorylation of SLP-76 by p-SYK (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Phosphorylation of SYK (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
DAP12 receptors:p-DAP12:SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
Recruitment of SYK to p-DAP12 (Gallus gallus)
DAP12 receptors:p-DAP12:SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
p85 regulatory unit of PI3K binds p-6Y-SYK (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
DAP12 Receptors:p-DAP12:p-6Y-SYK:PI3K [plasma membrane] (Gallus gallus)
DAP12 receptors:p-Y91,Y102-DAP12 dimer [plasma membrane] (Gallus gallus)
DAP12 receptors [plasma membrane] (Gallus gallus)
CD94:NKG2C:HLA-E [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
B2M [plasma membrane] (Gallus gallus)
External Reference Information
External Reference
UniProt:P21611
Gene Names
B2M
Reference Genes
BioGPS Gene:414830 B2M
ENSEMBL:ENSGALG00000002160
ENSEMBL:ENSGALG00010023281.1 B2M
ENSEMBL:ENSGALG00015014096 B2M
KEGG Gene (Gallus gallus):414830 B2M
Monarch:414830 B2M
NCBI Gene:414830 B2M
Reference Transcript
RefSeq:XM_015279077.1 B2M
RefSeq:NM_001001750.1 B2M
Other Identifiers
414830
GO:0002376
GO:0002474
GO:0002502
GO:0002503
GO:0002726
GO:0005198
GO:0005576
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005794
GO:0005829
GO:0005886
GO:0006879
GO:0006955
GO:0007155
GO:0007611
GO:0016192
GO:0019885
GO:0019886
GO:0023026
GO:0030154
GO:0031410
GO:0031902
GO:0034756
GO:0042605
GO:0042612
GO:0042613
GO:0042802
GO:0042803
GO:0042824
GO:0043226
GO:0048260
GO:0048856
GO:0050680
GO:0050768
GO:0050778
GO:0050870
GO:0050877
GO:0051289
GO:0055065
GO:0065003
GO:0071281
GO:0071316
GO:1990000
GO:1990712
GO:2000774
GO:2000978
GT_A_87_P075591
GT_A_87_P075596
GT_A_87_P075601
GT_A_87_P130368
GT_A_87_P130913
GT_Xhyb_Chicken_CN220056_1624
Gga.1328.1.S2_at
Participates
as a component of
CD1A:B2M [plasma membrane] (Gallus gallus)
CD1B:B2M [plasma membrane] (Gallus gallus)
CD1D:B2M [plasma membrane] (Gallus gallus)
Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Gallus gallus)
HLA-C Cw4 (group 2) [plasma membrane] (Gallus gallus)
HLA-E [plasma membrane] (Gallus gallus)
Other forms of this molecule
B2M [Golgi membrane]
B2M [ER to Golgi transport vesicle membrane]
B2M [early endosome lumen]
B2M [recycling endosome membrane]
B2M [phagocytic vesicle membrane]
B2M [tertiary granule lumen]
B2M [extracellular region]
B2M [endoplasmic reticulum lumen]
B2M [specific granule lumen]
Inferred From
B2M(21-119) [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001001750.1
,
XP_015134563.1
OpenTargets
ENSG00000166710
Ensembl
ENSGALG00010023281
,
ENSGALP00010034517
,
ENSGALT00010056777
PRO
P21611
PDB
6KX9
,
3O81
,
7WBG
,
4G42
,
4G43
,
6IRL
,
7WBI
,
4D0C
,
4D0B
,
3JVG
,
5AD0
,
6LHF
,
6LHG
,
6LHH
,
3P77
,
3BEW
,
4D0D
,
3BEV
,
3P73
,
5ACZ
,
2YEZ
,
4CVZ
,
4CVX
,
4CW1
,
5YMV
,
4E0R
,
5YMW
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