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NGF [extracellular region]
Stable Identifier
R-GGA-167034
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
extracellular region
Synonyms
A0A3Q2UGG2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
p75 NTR receptor-mediated signalling (Gallus gallus)
Cell death signalling via NRAGE, NRIF and NADE (Gallus gallus)
NRIF signals cell death from the nucleus (Gallus gallus)
TRAF6 binds to p75NTR:NRIF (Gallus gallus)
NGF ligand:p75NTR:NRIF [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:NRIF [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Gallus gallus)
NGF ligand:p75NTR:NRIF:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:NRIF [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NFG and proNGF binds to p75NTR (Gallus gallus)
NGF homodimer binds to p75NTR (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
p75NTR regulates axonogenesis (Gallus gallus)
Axonal growth stimulation (Gallus gallus)
NGF binding to p75NTR inactivates RHOA (Gallus gallus)
RHOA:GDP:ARHGDIA:NGFR:NGF [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
p75NTR signals via NF-kB (Gallus gallus)
NF-kB is activated and signals survival (Gallus gallus)
IKKbeta is activated (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:Phospho-IKK-beta [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
p75NTR recruits signalling complexes (Gallus gallus)
IKK-beta is recruited (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:IKK-beta [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
IRAK interacts with TRAF6 (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
MYD88 dissociates (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:MYD88:TRAF6 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:p-IRAK1:MYD88 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
TRAF6 is auto-ubiquitinated (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:polyubiquitinated TRAF6:p62 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
p62 is recruited and forms a complex with TRAF6 (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
p62 recruits an atypical PKC (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62:aPKCi [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6:p62 [plasma membrane] (Gallus gallus)
NGF ligand:p75NTR:Phospho-IRAK1:TRAF6 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
p75NTR interacts with RIP2 (Gallus gallus)
NGF:p75NTR:RIP2 [plasma membrane] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
mature NGF homodimer:p75NTR [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by NTRKs (Gallus gallus)
Expression and Processing of Neurotrophins (Gallus gallus)
NGF processing (Gallus gallus)
Pro-beta-NGF and mature beta-NGF are secreted (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Signaling by NTRK1 (TRKA) (Gallus gallus)
Activation of TRKA receptors (Gallus gallus)
TRKA activation by NGF (Gallus gallus)
Activated TrkA receptor internalizes to endosomes (Gallus gallus)
Activated TrkA receptor complex [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
The bound receptor dimerizes (Gallus gallus)
beta-NGF dimer:TrkA receptor [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
beta-NGF dimer:TrkA receptor dimer [plasma membrane] (Gallus gallus)
beta-NGF dimer:TrkA receptor [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
beta-NGF dimer binds to TrkA receptor (Gallus gallus)
beta-NGF dimer:TrkA receptor [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
PI3K/AKT activation (Gallus gallus)
Active IRS recruits PI3K to the plasma membrane and activates it (Gallus gallus)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Activated TrkA receptor:Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Gallus gallus)
Activated TrkA receptor:Phospho-IRS1/2 [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Retrograde neurotrophin signalling (Gallus gallus)
Axonal transport of NGF:Trk complexes (Gallus gallus)
Activated TrkA receptor complex:Clathrin-coated vesicle:Endophilin [plasma membrane] (Gallus gallus)
Activated TrkA receptor complex [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Signalling to ERKs (Gallus gallus)
Prolonged ERK activation events (Gallus gallus)
ARMS-mediated activation (Gallus gallus)
ARMS is phosphorylated by active TrkA receptor (Gallus gallus)
Active TrkA receptor:ARMS:Crk complex [plasma membrane] (Gallus gallus)
Activated TrkA receptor complex [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Gallus gallus)
Activated TrkA receptor complex [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
C3G stimulates nucleotide exchange on Rap1 (Gallus gallus)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Gallus gallus)
Activated TrkA receptor complex [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
Crk's SH3 domain engages C3G (Gallus gallus)
Active TrkA receptor:Phospho-ARMS:Crk complex [plasma membrane] (Gallus gallus)
Activated TrkA receptor complex [plasma membrane] (Gallus gallus)
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
NGF [extracellular region] (Gallus gallus)
External Reference Information
External Reference
UniProt:A0A3Q2UGG2
Reference Genes
ENSEMBL:ENSGALG00000002556
Participates
as a component of
mature beta-NGF homodimer [extracellular region] (Gallus gallus)
Other forms of this molecule
NGF(19-241) [extracellular region]
NGF [Golgi lumen]
NGF [cytosol]
NGF(19-241) [Golgi lumen]
Inferred From
NGF [extracellular region]
(Homo sapiens)
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