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MIB2 [cytosol]
Stable Identifier
R-GGA-1472879
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
E1BU56
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
Interaction of E3 with substrate and E2-Ub complex (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
Polyubiquitination of substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
Release of E3 from polyubiquitinated substrate (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
E3:K48-polyubiquitinated substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Ag-substrate:E3:E2:Ub [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
E3:Ub:substrate [cytosol] (Gallus gallus)
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
MIB2 binds CFLAR (Gallus gallus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 binds CYLD (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2:CYLD:UBE2D2 [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 ubiquitinates CFLAR (Gallus gallus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2:CYLD:UBE2D2 [cytosol] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Gallus gallus)
MIB2 [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:E1BU56
Reference Genes
ENSEMBL:ENSGALG00000001473
UCSC:E1BU56
Participates
as an input of
MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Gallus gallus)
MIB2 binds CFLAR (Gallus gallus)
MIB2 binds CYLD (Gallus gallus)
as a component of
TNF-α:TNFR1:TRADD:RIPK1:TRAF2:MIB2:Ub:UBE2D1 [plasma membrane] (Gallus gallus)
CFLAR:MIB2:Ub:UBE2D1 [cytosol] (Gallus gallus)
MIB2:CYLD:UBE2D2 [cytosol] (Gallus gallus)
TNF-α:TNFR1:TRADD:polyUb-RIPK1:TRAF2:MIB2 [plasma membrane] (Gallus gallus)
as an output of
MIB2 ubiquitinates CFLAR (Gallus gallus)
MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)
as a member of
E3 ligases in proteasomal degradation [cytosol] (Gallus gallus)
Other forms of this molecule
MIB2 [Golgi membrane]
Inferred From
MIB2 [cytosol]
(Homo sapiens)
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