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NRG1 [extracellular region]
Stable Identifier
R-GGA-1233225
Type
Set [DefinedSet]
Species
Gallus gallus
Compartment
extracellular region
Synonyms
Neuregulin-1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
PIP3 activates AKT signaling (Gallus gallus)
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
Activator:PI3K [plasma membrane] (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF/MAP kinase cascade (Gallus gallus)
RAS GEFs promote RAS nucleotide exchange (Gallus gallus)
RAS GEFs [plasma membrane] (Gallus gallus)
GRB2:SOS1:p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Gallus gallus)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ERBB2 (Gallus gallus)
Downregulation of ERBB2 signaling (Gallus gallus)
Downregulation of ERBB2:ERBB3 signaling (Gallus gallus)
RNF41 binds neuregulin-activated ERBB3 (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
RNF41 ubiquitinates activated ERBB3 (Gallus gallus)
NRG1/2:Ub-p-10Y-ERBB3:p-ERBB2 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-ERBB2 heterodimers:MATK [plasma membrane] (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Gallus gallus)
Heterodimers of p-ERBB2 dephosphorylated at Y1248 [plasma membrane] (Gallus gallus)
Phosphorylated p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Phosphorylated p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
ERBB2 Regulates Cell Motility (Gallus gallus)
Phosphorylated ERBB2 heterodimers bind MEMO1 (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-ERBB2 heterodimers:MEMO1 [plasma membrane] (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
ERBB3 binds neuregulins (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
PI3K events in ERBB2 signaling (Gallus gallus)
Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] (Gallus gallus)
NRG1/2:p-ERBB3:p-ERBB2:PIK3R1 [plasma membrane] (Gallus gallus)
Phosphorylated ERBB2:ERBB3 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
SHC1 events in ERBB2 signaling (Gallus gallus)
SHC1 phosphorylation by ERBB2 heterodimers (Gallus gallus)
SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-Y349,350-SHC1:Phosphorylated ERBB2 heterodimers [plasma membrane] (Gallus gallus)
p-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
SRC family kinases phosphorylate ERBB2 (Gallus gallus)
ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3:ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3:p-Y877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Trans-autophosphorylation of ERBB2 heterodimers (Gallus gallus)
ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3:ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-6Y-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Gallus gallus)
Autophosphorylated p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3:p-Y,877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:p-10Y-ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
p-Y877-ERBB2 heterodimers [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3:p-Y877-ERBB2 [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Signaling by ERBB4 (Gallus gallus)
ERBB4 forms heterodimers with ERBB3 (Gallus gallus)
ERBB4:ERBB3 heterodimer [plasma membrane] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
NRG1/2:ERBB3 [plasma membrane] (Gallus gallus)
NRG1/2 [extracellular region] (Gallus gallus)
NRG1 [extracellular region] (Gallus gallus)
Participants
members
NRG1 [extracellular region]
(Gallus gallus)
NRG1-10 [extracellular region]
(Gallus gallus)
Participates
as a member of
NRG1/2 [extracellular region] (Gallus gallus)
Inferred From
NRG1 [extracellular region]
(Homo sapiens)
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