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K48-ubiquitin (RPS27A) [cytosol]
Stable Identifier
R-GGA-1227810
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Gallus gallus)
Cytokine Signaling in Immune system (Gallus gallus)
Signaling by Interleukins (Gallus gallus)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Gallus gallus)
Regulation of signaling by CBL (Gallus gallus)
CBL ubiquitinates PI3K (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
TNFR2 non-canonical NF-kB pathway (Gallus gallus)
K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
Innate Immune System (Gallus gallus)
RLR (RIG-like receptor) mediated induction of IFN alpha/beta (Gallus gallus)
Negative Regulation of MDA5 signaling (Gallus gallus)
ITCH homolog downregulates MDA5/IPS1 signaling (Gallus gallus)
K48-linked polyubiquitin chain [cytosol] (Gallus gallus)
K48- Ubiquitin [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Deubiquitination (Gallus gallus)
Josephin domain DUBs (Gallus gallus)
ATXN3 deubiquitinates polyUb-PARK2 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
PARK2 autoubiquitinates (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
Ovarian tumor domain proteases (Gallus gallus)
OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
Ub-specific processing proteases (Gallus gallus)
USP10 deubiquitinates SNX3, CFTR (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP18 deubiquitinates TAK1:TAB1 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP20, USP33 deubiquitinate ADRB2 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP33 deubiquitinates CCP110,ARRB (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP4 deubiquitinate TRAF2,TRAF6 (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP5 cleaves polyubiquitin (Gallus gallus)
USP5:PolyUb [cytosol] (Gallus gallus)
PolyUb [cytosol] (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
USP8 deubiquitinates RNF128 (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
Programmed Cell Death (Gallus gallus)
Regulated Necrosis (Gallus gallus)
RIPK1-mediated regulated necrosis (Gallus gallus)
Regulation of necroptotic cell death (Gallus gallus)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Gallus gallus)
K48polyUb [cytosol] (Gallus gallus)
K48-Ub [cytosol] (Gallus gallus)
K48-ubiquitin (RPS27A) [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:P79781 RPS27A
Gene Names
RPS27A, UBA80
Chain
chain:1-76, chain:77-156
Reference Genes
BioGPS Gene:395796 RPS27A
ENSEMBL:ENSGALG00000036790 RPS27A
KEGG Gene (Gallus gallus):395796 RPS27A
Monarch:395796 RPS27A
NCBI Gene:395796 RPS27A
Reference Transcript
RefSeq:NM_204953.1 RPS27A
RefSeq:NM_001287205.1 RPS27A
Other Identifiers
395796
AAC60279
ENSGALG00000036790
ENSGALP00000050085
ENSGALT00000059625
EntrezGene:395796
EntrezGene:RPS27A
EntrezGene:RPS27A-201
Gga.471.1.S1_at
GO:0003674
GO:0003735
GO:0005198
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005840
GO:0006259
GO:0006281
GO:0006412
GO:0006464
GO:0006950
GO:0008150
GO:0009056
GO:0009058
GO:0016567
GO:0019899
GO:0019941
GO:0022627
GO:0031386
GO:0031625
GO:0032991
GO:0034641
GO:0043167
GO:0043226
GO:0046872
GT_A_87_P241238
GT_Xhyb_Chicken_CN224912_3082
IPR000626
IPR002906
IPR011332
IPR019954
IPR019956
IPR029071
IPR038582
NM_001287205
NP_001274134
PF00240
PF01599
PR00348
RPS27A
SM00213
SM01402
U67931
UPI00001713D2
Participant Of
hasMember
K48- Ubiquitin [cytosol]
K48-Ub [cytosol]
Other forms of this molecule
Ub-33-RPS27A(1-76) [mitochondrial outer membrane]
Ub-6-RPS27A(1-76) [mitochondrial outer membrane]
Ub-11-RPS27A(1-76) [mitochondrial outer membrane]
K63-ubiquitin (RPS27A) [cytosol]
ubiquitin (RPS27A) [cytosol]
Ub-63-RPS27A(1-76) [nucleoplasm]
ubiquitin (RPS27A) [nucleoplasm]
Ub-6-RPS27A(1-76) [nucleoplasm]
Ub-33-RPS27A(1-76) [nucleoplasm]
Ub-11-RPS27A(1-76) [nucleoplasm]
Ub-48-RPS27A(1-76) [nucleoplasm]
Ub-29-RPS27A(1-76) [nucleoplasm]
Ub-27-RPS27A(1-76) [nucleoplasm]
Ub-11-RPS27A(1-76) [cytosol]
Ub-27-RPS27A(1-76) [cytosol]
RPS27A(77-156) [cytosol]
K63-ubiquitin (RPS27A) [plasma membrane]
K63-ubiquitin (RPS27A) [endosome membrane]
K63-ubiquitin (RPS27A) [mitochondrial outer membrane]
RPS27A(1-76) [endosome membrane]
phospho-adenylatedlG76-RPS27A(1-76) [cytosol]
Ub-33-RPS27A(1-76) [cytosol]
Ub-6-RPS27A(1-76) [cytosol]
Ub-29-RPS27A(1-76) [cytosol]
N6-glycyl-L-lysine-RPS27A(1-76) [cytosol]
Ub-27-RPS27A(1-76) [mitochondrial outer membrane]
Ub-29-RPS27A(1-76) [mitochondrial outer membrane]
K48-ubiquitin (RPS27A) [mitochondrial outer membrane]
Inferred From
Ub-48-RPS27A(1-76) [cytosol] (Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine at 48
Coordinate
48
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_990284.1
,
NP_001274134.1
OpenTargets
ENSG00000143947
PRO
P79781
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