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VCP [cytosol]
Stable Identifier
R-GGA-1181251
Type
Protein [EntityWithAccessionedSequence]
Species
Gallus gallus
Compartment
cytosol
Synonyms
VCP, Q5ZMU9
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
KEAP1-NFE2L2 pathway (Gallus gallus)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Gallus gallus)
NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Gallus gallus)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Gallus gallus)
Deglycosylation complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Deubiquitination (Gallus gallus)
Ovarian tumor domain proteases (Gallus gallus)
YOD1 binds VCP (Gallus gallus)
VCP [cytosol] (Gallus gallus)
YOD1:VCP [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Neddylation (Gallus gallus)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Gallus gallus)
NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Gallus gallus)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Signal Transduction (Gallus gallus)
Signaling by Hedgehog (Gallus gallus)
Hedgehog ligand biogenesis (Gallus gallus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Gallus gallus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
SYVN1 ubiquitinates Hh C-terminal fragments (Gallus gallus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase cycle (Gallus gallus)
RHOH GTPase cycle (Gallus gallus)
RHOH binds effectors at the plasma membrane (Gallus gallus)
RHOH effectors [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
RHOH:GTP:RHOH effectors [plasma membrane] (Gallus gallus)
RHOH effectors [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Gallus gallus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
ERAD complex [endoplasmic reticulum membrane] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
VCP [cytosol] (Gallus gallus)
External Reference Information
External Reference
UniProt:Q5ZMU9
Gene Names
VCP
Reference Genes
BioGPS Gene:427410 VCP
ENSEMBL:ENSGALG00000001986
ENSEMBL:ENSGALG00010011335.1 VCP
KEGG Gene (Gallus gallus):427410 VCP
Monarch:427410 VCP
NCBI Gene:427410 VCP
Reference Transcript
RefSeq:NM_001044664.1 VCP
Other Identifiers
427410
GO:0000278
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005783
GO:0005829
GO:0006886
GO:0006914
GO:0007010
GO:0008289
GO:0016787
GO:0016887
GO:0030163
GO:0030433
GO:0030970
GO:0031593
GO:0033554
GO:0034098
GO:0043226
GO:0051228
GO:0071712
GO:0097352
GO:0140657
GT_A_87_P285303
GT_A_87_P298598
GgaAffx.11388.1.S1_at
Participates
as a candidate of
RHOH effectors [cytosol] (Gallus gallus)
as an input of
YOD1 binds VCP (Gallus gallus)
as a component of
YOD1:VCP [cytosol] (Gallus gallus)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Gallus gallus)
VCP hexamer [cytosol] (Gallus gallus)
Other forms of this molecule
VCP [cytosol]
VCP [nucleoplasm]
VCP [azurophil granule lumen]
VCP [secretory granule lumen]
VCP [extracellular region]
VCP [ficolin-1-rich granule lumen]
Inferred From
VCP [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001038129.1
OpenTargets
ENSG00000165280
Ensembl
ENSGALT00010027142
,
ENSGALG00010011335
,
ENSGALP00010015445
PRO
Q5ZMU9
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8AYS8
2
KCNU1 [plasma membrane]
(R-GGA-2534368)
KCNMA1 [plasma membrane]
(R-GGA-418462)
0.499
3
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