Activated thrombin (factor IIa) cleaves PAR3,4, activating them

Stable Identifier
R-GGA-114697
Type
Reaction [transition]
Species
Gallus gallus
Compartment
Synonyms
Thrombin-mediated activation of Proteinase-activated receptors
Locations in the PathwayBrowser
General
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Participants
Participates
Catalyst Activity

serine-type endopeptidase activity of activated thrombin (factor IIa) [extracellular region]

Inferred From
Created
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