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PA [endosome lumen]
Stable Identifier
R-FLU-189131
Type
Protein [EntityWithAccessionedSequence]
Species
Influenza A virus
Compartment
endosome lumen
GO Cellular Component
host cell endosome lumen
(0072493)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Entry of Influenza Virion into Host Cell via Endocytosis (Homo sapiens)
Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion (Homo sapiens)
Influenza A Viral Particle [endosome lumen] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Fusion and Uncoating of the Influenza Virion (Homo sapiens)
Fusion of the Influenza Virion to the Host Cell Endosome (Homo sapiens)
Concerted hemagglutinin pore formation (Homo sapiens)
Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane [endocytic vesicle membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Conformation change in hemagglutinin freeing the fusion peptide of HA2 (Homo sapiens)
Influenza A Viral Particle With A Fusion Competent HA2 [endosome lumen] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Influenza A Viral Particle [endosome lumen] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Fusion of the influenza virion HA2 protein transmembrane domain to the host cell endosome membrane (Homo sapiens)
Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane [endocytic vesicle membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Influenza A Viral Particle With A Fusion Competent HA2 [endosome lumen] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Uncoating of the Influenza Virion (Homo sapiens)
Ribonucleoprotein release from M1 proteins (Homo sapiens)
Acidified Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Virion-associated M2 protein mediated ion infusion (Homo sapiens)
Acidified Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
PA [endosome lumen] (Influenza A virus)
External Reference Information
External Reference
UniProt:P03433 PA
Gene Names
PA
Chain
chain:1-716
Reference Genes
BioGPS Gene:956535 PA
KEGG:vg:956535 PA
Monarch:956535 PA
NCBI Gene:956535 PA
UCSC:P03433 PA
Reference Transcript
RefSeq:NC_002022.1 PA
Participates
as a component of
Ribonucleoprotein (RNP) Complex [endosome lumen] (Influenza A virus)
Other forms of this molecule
PA [extracellular region]
PA [cytosol]
PA [nucleoplasm]
Cross References
ZINC - Investigational
PA_I34A1
ZINC - Substances
PA_I34A1
ZINC target
P03433
PRO
P03433
ZINC - Predictions - Purchasable
PA_I34A1
PDB
4YYL
,
4ZHZ
,
5JHV
,
5JHT
,
5FDG
,
5I13
,
7XGC
,
2ZNL
,
4ZQQ
,
4ZI0
,
5FDD
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03431 PB1
4
PB1 [extracellular region]
(R-FLU-169246)
PB1 [endosome lumen]
(R-FLU-189137)
PB1 [cytosol]
(R-FLU-195940)
PB1 [nucleoplasm]
(R-FLU-188843)
0.819
6
UniProt:P03466 NP
6
NP [Golgi membrane]
(R-FLU-195740)
NP [plasma membrane]
(R-FLU-195752)
NP [extracellular region]
(R-FLU-169251)
NP [endosome lumen]
(R-FLU-189141)
NP [cytosol]
(R-FLU-188848)
NP [nucleoplasm]
(R-FLU-188832)
0.586
3
UniProt:P03485 M
6
M1 [plasma membrane]
(R-FLU-195782)
M1 [extracellular region]
(R-FLU-169241)
M1 [endocytic vesicle membrane]
(R-FLU-189168)
M1 [endosome lumen]
(R-FLU-189155)
M1 [cytosol]
(R-FLU-169073)
M1 [nucleoplasm]
(R-FLU-186959)
0.573
2
UniProt:P03428 PB2
5
PB2 [extracellular region]
(R-FLU-169238)
PB2 [endosome lumen]
(R-FLU-189140)
PB2 [cytosol]
(R-FLU-188851)
PB2 [cytosol]
(R-FLU-195946)
PB2 [nucleoplasm]
(R-FLU-188857)
0.528
2
UniProt:P49736 MCM2
1
MCM2 [nucleoplasm]
(R-HSA-68557)
0.462
2
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