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Carmustine produces interstrand crosslinks in E. coli DNA
Stable Identifier
R-ECO-9750081
Type
Reaction [omitted]
Species
Escherichia coli
Compartment
nucleoplasm
ReviewStatus
5/5
General
SBML
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BioPAX
Level 2
Level 3
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SBGN
Carmustine produces interstrand crosslinks in E. coli double-stranded DNA (dsDNA) (Kohn et al. 1977).
Literature References
PubMed ID
Title
Journal
Year
851960
Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas
Kohn, KW
Cancer Res
1977
Participants
Input
carmustine [nucleoplasm]
dsDNA [nucleoplasm]
(Escherichia coli)
Output
ICL-DNA [nucleoplasm]
(Escherichia coli)
Orthologous Events
Anti-cancer drugs generate DNA interstrand crosslinks (Homo sapiens)
Authored
Orlic-Milacic, M (2021-02-01)
Reviewed
Kadambat Nair, S (2021-07-28)
Created
Orlic-Milacic, M (2021-08-09)
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