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Flagellin [plasma membrane]
Stable Identifier
R-ECO-1181207
Type
Protein [EntityWithAccessionedSequence]
Species
Escherichia coli
Compartment
plasma membrane
GO Cellular Component
host cell plasma membrane
(0020002)
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of Immune System (Homo sapiens)
Diseases associated with the TLR signaling cascade (Homo sapiens)
IRAK4 deficiency (TLR5) (Homo sapiens)
Defective IRAK4 does not form a complex with MyD88 within the TLR5 complex (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK4 deficiency blocks formation of the MyD88-IRAK4 Myddosome in the TLR5 pathway (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 deficiency (TLR5) (Homo sapiens)
Defective MyD88 does not oligomerize within the complex of activated TLR5 (Homo sapiens)
MyD88 variant:TLR5:bacterial flagellin [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex (Homo sapiens)
IRAK1 or IRAK2 :p-IRAK4:MyD88 oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
hp-IRAK1:activated IRAK4:MyD88oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
TRAF6 binds to hp- IRAK1 or p-IRAK2 (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
Flagellin binds to TLR5 (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex (Homo sapiens)
IRAK1 or IRAK2 :p-IRAK4:MyD88 oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)
IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
hp-IRAK1:activated IRAK4:MyD88oligomer:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 forms a complex with the activated TLR receptor (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)
MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
IRAK2:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
TRAF6 binds to hp- IRAK1 or p-IRAK2 (Homo sapiens)
TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane] (Homo sapiens)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane] (Homo sapiens)
p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
oligo-MyD88:activated TLR5 or 10 [plasma membrane] (Homo sapiens)
Activated TLR5 or TLR10 homodimer [plasma membrane] (Homo sapiens)
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Flagellin [plasma membrane] (Escherichia coli)
External Reference Information
External Reference
UniProt:P04949 fliC
Gene Names
fliC, flaF, hag, b1923, JW1908
Chain
initiator methionine:, chain:2-498
Reference Genes
BioGPS Gene:949101 fliC
KEGG Gene (Escherichia coli K-12 MG1655):b1923 fliC
KEGG Gene (Escherichia coli K-12 W3110):JW1908 fliC
Monarch:949101 fliC
NCBI Gene:949101 fliC
Reference Transcript
RefSeq:NC_000913.3 fliC
RefSeq:NZ_LN832404.1 fliC
Participates
as a component of
TLR5 homodimer:bacterial flagellin [plasma membrane] (Homo sapiens)
Other forms of this molecule
Flagellin [extracellular region]
Disease
Name
Identifier
Synonyms
bacterial infectious disease
DOID:104
Cross References
RefSeq
NP_416433.1
,
WP_000079739.1
PRO
P04949
PDB
8CXM
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q29XT7 Q29XT7
0.65
5
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